Houston, TXNCT05006430Now EnrollingIRB Ready

Alcoholic Hepatitis Clinical Trial in Houston, TX

Access cutting-edge alcoholic hepatitis treatment through this clinical trial at a research site in Houston. Study-provided care at no cost to qualified participants.

Sponsored by Prasun Kumar Jalal

Quick Self-Assessment

See if you qualify for this Houston location

Preparing your pre-screening questions…

Expert Care in Houston

Access alcoholic hepatitis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related alcoholic hepatitis treatment provided free

Apply for This Houston Location

Check if you qualify for this alcoholic hepatitis clinical trial in Houston, TX

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Houston

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Houston site if eligible
  4. 4Begin participation

About This Alcoholic Hepatitis Study in Houston

This is a single center, randomized, parallel assignment, and double-blind placebo-controlled pilot study to characterize the intestinal microbiome in patients with severe Alcoholic Hepatitis (SAH) and evaluate the safety and the trends in improvement of diversity of intestinal microbiome following administration of lyophilized capsules containing microbiota suspension from well screened health donors. The study aims to enroll 50 patients with SAH who will be randomly assigned in 1:1 where 25 patients will be assigned to receive orally administered lyophilized PRIM-DJ2727 and Standard of Care (SOC) and the other 25 patients will be assigned to receive placebo and SOC for 4 weeks.

Sponsor: Prasun Kumar Jalal

Who Can Participate

Inclusion Criteria

Any gender; male or female; aged 18- 75 years old.
Severe alcoholic hepatitis defined as 2.1 Onset of jaundice within prior 8 weeks. 2.2 Ongoing alcohol consumption of \>40 g/day (3 drinks) in females or \>60 g/day (4 drinks) in males for 6 months or more, with less than 60 days of abstinence before the onset of jaundice. 2.3 Aspartate aminotransferase \>50, Aspartate aminotransferase/Alanine aminotransferase ratio \> 1.5, BUT both values \<400 IU/L. 2.4 Serum total bilirubin \>3.0 mg/dl. 2.5 MELD score \>15 and/or Maddrey DF score of ≥32.

Exclusion Criteria

Non-alcoholic related liver diseases.
Patients with swallowing dysfunction at risk of aspiration.
Patients at risk for or with known anatomic or functional gastrointestinal (GI) obstruction or who have undergone major intra-abdominal surgery in the last year.
Patients who have undergone placement of a portosystemic shunt, infection of which may require prolonged antibiotics.
Patients with any congenital or acquired immunodeficiency (Other than liver disease)
Uncontrolled infections, sepsis, or GI bleeding.
Presence of cancer especially patients with skin cancer who is receiving or may receive systemic chemotherapy or immunotherapy during the study period.
Underlying disease that might be exacerbated by proposed treatments (e.g. HCV, HBV, HIV, TB).
Serum creatinine \>2.5 mg/dl at presentation.
Pregnant and breastfeeding patients.
Active use drug addiction.
PI thinks their participation would pose a health risk e.g. patients with very severe AH with MELD score \>30 or Maddrey DF \> 60 or patient will be getting liver transplantation imminently.
Any other major illness/ condition that in the investigators judgment, will substantially increase the risk to the participant.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Houston?

Yes, this clinical trial (NCT05006430) has an active research site in Houston, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Alcoholic Hepatitis Treatment Options in Houston, TX

If you're searching for alcoholic hepatitis treatment options in Houston, TX, this clinical trial (NCT05006430) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Houston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced alcoholic hepatitis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all alcoholic hepatitis clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Houston, TX