Cleveland, OHNCT05018481Now EnrollingIRB Ready

Alcoholic Hepatitis Clinical Trial in Cleveland, OH

Access cutting-edge alcoholic hepatitis treatment through this clinical trial at a research site in Cleveland. Study-provided care at no cost to qualified participants.

Sponsored by The Cleveland Clinic

Quick Self-Assessment

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Preparing your pre-screening questions…

Expert Care in Cleveland

Access alcoholic hepatitis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related alcoholic hepatitis treatment provided free

Apply for This Cleveland Location

Check if you qualify for this alcoholic hepatitis clinical trial in Cleveland, OH

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Cleveland

    Convenient for OH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Cleveland site if eligible
  4. 4Begin participation

About This Alcoholic Hepatitis Study in Cleveland

Eligible participants will be asked to take a placebo/treatment capsule for 90 days and participate in two in-person study visits, one at the start of the 90 days and the second at the completion of study supplement administration. Both visits will include a physical exam, clinical labs, body composition measurements, muscle strength tests, questionnaires, and urine and stool collections. Additionally, a sugar cocktail will be consumed to measure gut permeability and a muscle biopsy will be collected. The day after the visits, you will need to return to drop off the 24-hour urine collection. Two phone visits will be performed in between the in-person visits at day 30 and 60 where you will be asked a series of questionnaires as well as asked about study supplement compliance.

Sponsor: The Cleveland Clinic

Who Can Participate

Inclusion Criteria

• Clinical diagnosis of alcoholic hepatitis defined as:
Regular consumption of alcohol with an intake of \>60 g daily or \>420 g weekly on average for men and \>40 g daily or \>280 g weekly on average for women for 6 months or more AND
Serum total bilirubin \>3 mg/dL
AST \>50 IU/I; AST:ALT ratio \>1.5; Both AST and ALT \<400 IU/I OR Histologic evidence of AH.

Exclusion Criteria

Pregnant or breastfeeding women
Patients with gastrointestinal bleeding within 2 weeks
Active infection (positive blood or ascitic fluid culture)
Overt encephalopathy
Renal failure and/or on dialysis
Medications that alter muscle protein metabolism
Other end-stage organ diseases
Solid organ or hematopoietic transplantation
Active alcohol withdrawal or ongoing participation in a Clinical Institute Withdrawal Assessment (CIWA) protocol
History of recent upper gastrointestinal resection within past 6 months
Acute or chronic liver disease due to other active causes, in addition to alcoholic liver disease
Inability to provide consent
Creatinine \>2mg/dL
Platelets \<60,000k/ul
PT/INR \>1.7
Presence of pedal edema
Use of anti-platelet/anticoagulation drugs or medications that interfere with blood clotting

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Cleveland?

Yes, this clinical trial (NCT05018481) has an active research site in Cleveland, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Alcoholic Hepatitis Treatment Options in Cleveland, OH

If you're searching for alcoholic hepatitis treatment options in Cleveland, OH, this clinical trial (NCT05018481) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Cleveland research site is actively enrolling participants for this clinical trial. You'll receive care from experienced alcoholic hepatitis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all alcoholic hepatitis clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Cleveland, OH