Birmingham, ALNCT07135427Now EnrollingIRB Ready

Alpha 1-Antitrypsin Clinical Trial in Birmingham, AL

Access cutting-edge alpha 1-antitrypsin treatment through this phase 4 clinical trial at a research site in Birmingham. Study-provided care at no cost to qualified participants.

Sponsored by University of Alabama at Birmingham

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Expert Care in Birmingham

Access alpha 1-antitrypsin specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related alpha 1-antitrypsin treatment provided free

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Check if you qualify for this alpha 1-antitrypsin clinical trial in Birmingham, AL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Birmingham

    Convenient for AL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Birmingham site if eligible
  4. 4Begin participation

About This Alpha 1-Antitrypsin Study in Birmingham

The goal of this study is to learn whether patients who have a genetic mutation in the genes that cause alpha 1 antitrypsin deficiency also have genetic variation in nearby genes that can increase risk for reduced immune function and respiratory infections. To investigate this hypothesis, we will compare immune responses to the 20-valent pneumococcal conjugate vaccine (PCV20, Pfizer) between participants who have one abnormal copy of the SERPINA1 gene and either no COPD exacerbations, vs those with 2 or more COPD exacerbations in the past year.

Sponsor: University of Alabama at Birmingham

Who Can Participate

Inclusion Criteria

Adults who are heterozygous for a SERPINA1 Z allele
Have either had no COPD exacerbations or 2 or more exacerbations in the previous year
Has not received a pneumococcal conjugate vaccine within the past 5 years, or has only received the pneumococcal polysaccharide vaccine in the past

Exclusion Criteria

Received a pneumococcal conjugate vaccine within the past 5 years
Known allergy, severe adverse reaction, or other sensitivity to pneumococcal conjugate vaccines

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Birmingham?

Yes, this clinical trial (NCT07135427) has an active research site in Birmingham, AL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Alpha 1-Antitrypsin Treatment Options in Birmingham, AL

If you're searching for alpha 1-antitrypsin treatment options in Birmingham, AL, this clinical trial (NCT07135427) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Birmingham research site is actively enrolling participants for this phase 4 clinical trial. You'll receive care from experienced alpha 1-antitrypsin specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all alpha 1-antitrypsin clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Birmingham, AL