Roslindale, MANCT06821568Now EnrollingIRB Ready

Alzheimer Disease and Related Dementias Clinical Trial in Roslindale, MA

Access cutting-edge alzheimer disease and related dementias treatment through this clinical trial at a research site in Roslindale. Study-provided care at no cost to qualified participants.

Sponsored by Hebrew SeniorLife

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Expert Care in Roslindale

Access alzheimer disease and related dementias specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related alzheimer disease and related dementias treatment provided free

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Check if you qualify for this alzheimer disease and related dementias clinical trial in Roslindale, MA

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Why Participate?

  • No-Cost Study Care

  • Local to Roslindale

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Roslindale site if eligible
  4. 4Begin participation

About This Alzheimer Disease and Related Dementias Study in Roslindale

The objective of this study is to determine the effects of a 6-month, home-based personalized transcranial direct current stimulation (tDCS) intervention targeting the left dorsolateral prefrontal cortex on cognitive function, dual task standing and walking, and other metrics of mobility in older adults with motoric cognitive risk syndrome (MCR).

Sponsor: Hebrew SeniorLife

Who Can Participate

Inclusion Criteria

Men and women
Age 65-90 years
Subjective cognitive complaints as defined by a 'Yes' response to "Do you feel that you have more problems with memory than most?" or a 'No' response to "is your mind as clear as it used to be?"
Montreal Cognitive Assessment (MoCA) score ≥21
Slow gait speed as measured by averaging two 4-Meter walks and defined as a usual walking speed one standard deviation below age and sex-adjusted means.
Absence of significant disability as defined by the ability to walk over the instrumented gait mat unassisted (e.g., able to walk without any walking aids for at least 2 minutes non-stop) and preserved activities of daily living as defined by a score of less than 9 on the Functional Activities Questionnaire.
Identification of an eligible informant
Identification of a willing and able tDCS-administrator; i.e., a study partner to lead the administration of home-based transcranial direct current stimulation (tDCS)
Access to reliable WiFi in the participant's home

Exclusion Criteria

Formal education less than the 8th grade
Previous physician diagnosis of dementia
Any current diagnosis of a major psychiatric disorder (e.g., schizophrenia, bipolar disorder, major depressive disorder)
Evidence of moderate-to-severe depressive symptoms defined by a score of ≥9 on the 15-item Geriatric Depression Scale
History of head trauma resulting in prolonged loss of consciousness
History of fainting spells of unknown or undetermined etiology that might constitute seizures
History of seizures, diagnosis of epilepsy, or immediate (first-degree relative) family history of epilepsy except for a single seizure of benign etiology (e.g. febrile seizures) in the judgment of a board-certified neurologist
Hospitalization within the past three months due to acute illness, or as the result of a musculoskeletal injury significantly affecting gait or balance
Any unstable medical condition or chronic (particularly) uncontrolled medical conditions that may cause a medical emergency in case of a provoked seizure (cardiac malformation, cardiac dysrhythmia, asthma, etc.) or study complication
Substance use disorders within the past six months
A hairstyle or headdress that prevents electrode contact with the scalp or would interfere with the stimulation (for example thick braids, hair weave, afro, wig)
Chronic vertigo
Myocardial infarction within the past 6 months
Active cancer for which chemo-/radiation therapy is being received
Legal blindness
Visual hallucinations (history or self-report)
Contraindications to MRI or tDCS, including unprovoked seizure within the past two years, risk of ferromagnetic objects anywhere in the body, self-reported presence of specific implanted medical devices (e.g., deep brain stimulator, medication infusion pump, cochlear implant, pacemaker, etc.), the presence of any active dermatological condition, such as eczema, on the scalp, etc. as outlined by current recommendations for noninvasive brain stimulation endorsed by the International Federation for Clinical Neurophysiology.
History of REM sleep behavior disorder (RBD), often an early sign of Parkinson's disease
Medications and medical history will be reviewed by the responsible covering physician and a decision about inclusion will be made based on the participant's past medical history, drug dose, history of recent medication changes or duration of treatment, and combination with other CNS active drugs.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Roslindale?

Yes, this clinical trial (NCT06821568) has an active research site in Roslindale, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Alzheimer Disease and Related Dementias Treatment Options in Roslindale, MA

If you're searching for alzheimer disease and related dementias treatment options in Roslindale, MA, this clinical trial (NCT06821568) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Roslindale research site is actively enrolling participants for this clinical trial. You'll receive care from experienced alzheimer disease and related dementias specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all alzheimer disease and related dementias clinical trials near you to find additional studies recruiting in your area.

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