NCT05874297 · Fred Hutchinson Cancer Center
Online Nutrition Education to Decrease the Side Effects of Chemotherapy in Patients With Breast Cancer
(ONE)
What this study is about
This trial tests an online nutrition education program focused on decreasing nutrition-related side effects of chemotherapy in patients with breast cancer. Patients undergoing chemotherapy are at risk for complications such as diarrhea or constipation which can lead to poor nutritional intake and malabsorption of nutrients.
View original scientific description
This trial tests an online nutrition education program focused on decreasing nutrition-related side effects of chemotherapy in patients with breast cancer. Patients undergoing chemotherapy are at risk for complications such as diarrhea or constipation which can lead to poor nutritional intake and malabsorption of nutrients. This study is testing the effects of information delivered via the Cook for Your Life website in conjunction with standard clinical care to improve symptom management during chemotherapy treatment for breast cancer, which could serve as a new model for supportive oncology care.
Interventions
OTHER
Best Practice
Receive standard of care
BEHAVIORAL
Internet-Based Intervention
Access to enhanced Cook for your life website
OTHER
Questionnaire Administration
Ancillary studies
Primary outcome measures
Accrual rate
Time frame: ~4 months
Accrual rate to the study.
Use of cook for your life website pages (adherence: visiting website) will be measured via Google analytics
Time frame: ~4 months
Google analytics will be used to identify whether participants visit the website.
Use of cook for your life website pages (adherence: webpages viewed) will be measured via Google analytics
Time frame: ~4 months
Google analytics will be used to identify what webpages participants view.
Time of use of cook for your life website (adherence: total time) will be measured via Google analytics
Time frame: ~4 months
Google analytics will be used to measure how much total time spent on the website.
Time of use of cook for your life website (adherence: time per webpage) will be measured via Google analytics
Time frame: ~4 months
Google analytics will be used to measure time spent per webpage visited.
User pathways of cook for your life website (adherence) will be measured via Google analytics
Time frame: ~4 months
Google analytics will be used to determine the order/sequence of webpages participants follow to navigate through the website.
Participant retention will be measured via participants competing surveys at all timepoints
Time frame: ~4 months
The number of participants who complete all study activities through the end of chemotherapy.
Acceptability of cook for your life website will be measured via an exit interview
Time frame: ~4 months
Participant acceptability of cook for your life website will be assessed via a short semi-structured exit interview.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- 18 years of age or older.
- Stage I-III breast cancer.
- Current breast cancer patients scheduled to receive ddAC-T(+/-C), TCHP, or TCPembro-AC chemotherapy at Fred Hutch South Lake Union (can enroll prior to receipt of 2nd cycle).
- Not pregnant and no plan to become pregnant during chemotherapy treatment.
- Ability to speak and read English.
- Access to smartphone, tablet, or computer and Internet.
- Willing and able to complete all study activities through the end of chemotherapy, including completing online questionnaires and telephone assessments.
- Women must not be pregnant at time of enrollment based on self-report.
- Able to understand and willing to sign written informed electronic (e) consent in English.
Where
- Seattle, Washington
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Jul 16, 2026 · Source of record for eligibility and locations