Jacksonville, FLNCT05746325Now EnrollingIRB Ready

Anatomic Stage IV Breast Cancer AJCC v8 Clinical Trial in Jacksonville, FL

Access cutting-edge anatomic stage iv breast cancer ajcc v8 treatment through this clinical trial at a research site in Jacksonville. Study-provided care at no cost to qualified participants.

Sponsored by Mayo Clinic

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Expert Care in Jacksonville

Access anatomic stage iv breast cancer ajcc v8 specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related anatomic stage iv breast cancer ajcc v8 treatment provided free

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Check if you qualify for this anatomic stage iv breast cancer ajcc v8 clinical trial in Jacksonville, FL

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Why Participate?

  • No-Cost Study Care

  • Local to Jacksonville

    Convenient for FL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Jacksonville site if eligible
  4. 4Begin participation

About This Anatomic Stage IV Breast Cancer AJCC v8 Study in Jacksonville

This clinical trial evaluates the safety and feasibility of tumor treating fields (TTF) in the treatment of spinal leptomeningeal disease in patients with breast or lung cancer that has spread from where it first started (primary site) to other places in the body (metastatic). Patients wear the portable Novo TTF-200T device that produces electric fields to target areas on the body to stop the growth of tumor cells. The information from this study will help researchers develop a better treatment for leptomeningeal metastases in the future.

Sponsor: Mayo Clinic

Who Can Participate

Inclusion Criteria

Prior tissue diagnosis of breast cancer or lung cancer
Confirmed diagnosis of leptomeningeal metastases (LM) with positive cerebrospinal fluid (CSF) cytology for malignancy and meningeal enhancement (type 1A, 1B, and 1C)
Radiographic evidence on MRI of leptomeningeal enhancement within the cervical, thoracic or lumbar spine on spinal MRI
Life expectancy of at least 6 weeks
Eastern Cooperative Oncology Group (ECOG) performance status of 0, 1, 2, or 3
Recovery from any neurotoxic effects of prior therapy
Platelet count greater than 25 x 10\^9/L
Absolute neutrophil count (ANC) greater than 0.5 x 10\^9/L
Patients must have adequate liver function, total bilirubin \< 2.5 mg/dL, unless elevated total bilirubin is due to elevated indirect bilirubin from known Gilbert's disease, aspartate aminotransferase (AST) =\< 3.5 times upper limits of normal; adequate renal function \[calculated estimated glomerular filtration rate (eGFR) \>= 30 mL/min/ body surface area (BSA)\]
Patients or legal medical representative must provide written informed consent
Patients must have suitable body habitus for placement of transducer arrays
Patients must be willing to wear the device for at least 18 hours a day (averaged over monthly)
Patients must be willing to return for the scheduled evaluations and perform the required assessments
Patients are without other disease or situation which would significantly compromise adequate assessment of safety and feasibility of the TTF
Patient willing to start a study treatment with TTF =\< 14 days from registration

Exclusion Criteria

Concomitant therapy:
Must not be receiving concurrent high-dose methotrexate (\>= 3 g/m\^2), high dose thiotepa, or high-dose cytarabine (\>= 3 g/m\^2). Any other systemic chemotherapy, targeted treatment, hormonal or immunotherapy directed at the primary systemic malignancy is permitted
Must not have received radiation therapy (RT) to the brain or spinal cord within 2 weeks of initiation of TTF
Must be at least 1 week from cessation of any prior intrathecal chemotherapy
Women of childbearing age who are pregnant or lactating. (Male and female patients who are fertile must be willing to use an effective means of birth control to avoid pregnancy)
Patients with uncontrolled or untreated infection including active hepatitis, and human immunodeficiency virus (HIV)
Patients receiving any other investigational agents and must not have received any other investigational agent within 14 days prior to registration. The 14-day period should be extended if the investigational agent is known to have delayed toxicity
Patients known to be allergic to the hydrophilic gel utilized for transducer attachment
Patients with surgical hardware within the planned area of treatment in the spine (e.g., titanium rods, screws, fixation devices)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Jacksonville?

Yes, this clinical trial (NCT05746325) has an active research site in Jacksonville, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Anatomic Stage IV Breast Cancer AJCC v8 Treatment Options in Jacksonville, FL

If you're searching for anatomic stage iv breast cancer ajcc v8 treatment options in Jacksonville, FL, this clinical trial (NCT05746325) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Jacksonville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced anatomic stage iv breast cancer ajcc v8 specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all anatomic stage iv breast cancer ajcc v8 clinical trials near you to find additional studies recruiting in your area.

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