Richmond, VANCT07848828Now EnrollingIRB Ready

Androgen Deprivation Therapy Clinical Trial in Richmond, VA

Access cutting-edge androgen deprivation therapy treatment through this phase 4 clinical trial at a research site in Richmond. Study-provided care at no cost to qualified participants.

Sponsored by Virginia Commonwealth University

Quick Self-Assessment

See if you qualify for this Richmond location

Preparing your pre-screening questions…

Expert Care in Richmond

Access androgen deprivation therapy specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related androgen deprivation therapy treatment provided free

Apply for This Richmond Location

Check if you qualify for this androgen deprivation therapy clinical trial in Richmond, VA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Richmond

    Convenient for VA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Richmond site if eligible
  4. 4Begin participation

About This Androgen Deprivation Therapy Study in Richmond

This study plans to learn more about contributors to high blood pressure in men who undergo androgen deprivation therapy (ADT) to treat prostate cancer. Prostate cancer is the most common non-skin cancer in men, affecting approximately 1 in 8 American men and its primary treatment is through the use of ADT. However, ADT increases the likelihood of developing heart disease including high blood pressure. This study will determine if dysfunction of the nervous system and/or kidneys occurs in men undergoing ADT, as these systems play a significant role in control of blood pressure. The results from this study will help us understand the ways in which ADT contributes to heart disease and help us develop therapies to prevent heart disease in prostate cancer survivors.

Sponsor: Virginia Commonwealth University

Who Can Participate

Inclusion Criteria

age 40+ years;
resting blood pressure \<140/90 mmHg;
fasted blood glucose \<126 mg/dL;
testosterone ≥400 ng/dL;
sedentary to recreationally active;
nonsmokers;
healthy as determined by medical history, physical exam, blood and urine chemistries and resting and exercise ECG during a physician supervised graded exercise treadmill test OR recent diagnosis of non-metastatic prostate cancer with plans to undergo androgen deprivation therapy;
PSA \<4.00 ng/dL if in the non-cancer group;
Gleason Score ≤7 if in the prostate cancer group;
no use of medications that might influence cardiovascular function (e.g., antihypertensives, lipid-lowering medications);
willing and able to be on GnRHagonist and AR inhibitor;
not taking antioxidant vitamins, corticosteroids, or anti-inflammatory medications, or willing to stop use for four weeks prior to the start of the study;
not using exogenous sex hormones for at least one year

Exclusion Criteria

-acute liver disease;
chronic kidney disease, serum creatinine \>1.3 mg/dL, macroalbuminuria \>300 mg/g of proteinuria
pre-existing or active cardiac, renal or hepatic disease, epilepsy or other seizure disorder;
diabetes, active or chronic infection, disease that affects the nervous system;
Gleason Score ≥8;
thyroid dysfunction, defined as ultrasensitive TSH \<0.5 or \>5.0 mU/L, volunteers with abnormal TSH values will be re-considered for participation after follow-up evaluation by the PCP with initiation or adjustment of thyroid hormone replacement;
tobacco use within the previous 12 months

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Richmond?

Yes, this clinical trial (NCT07848828) has an active research site in Richmond, VA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Androgen Deprivation Therapy Treatment Options in Richmond, VA

If you're searching for androgen deprivation therapy treatment options in Richmond, VA, this clinical trial (NCT07848828) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Richmond research site is actively enrolling participants for this phase 4 clinical trial. You'll receive care from experienced androgen deprivation therapy specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all androgen deprivation therapy clinical trials near you to find additional studies recruiting in your area.

More Rheumatoid Arthritis Trials in Richmond, VA

See all rheumatoid arthritis clinical trials recruiting in Richmond — not just this study.

Browse Rheumatoid Arthritis Trials in Richmond →

Browse More Trials by Condition

Rheumatoid Arthritis TrialsAll Conditions →

Ready to Join in Richmond?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Richmond, VA