Austin, TXNCT07391605Now EnrollingIRB Ready

Antisynthetase Syndrome Clinical Trial in Austin, TX

Access cutting-edge antisynthetase syndrome treatment through this clinical trial at a research site in Austin. Study-provided care at no cost to qualified participants.

Sponsored by Cartesian Therapeutics

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Expert Care in Austin

Access antisynthetase syndrome specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related antisynthetase syndrome treatment provided free

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Check if you qualify for this antisynthetase syndrome clinical trial in Austin, TX

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Austin

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Austin site if eligible
  4. 4Begin participation

About This Antisynthetase Syndrome Study in Austin

This is a randomized, double-blind, placebo-controlled phase 2 study to evaluate the efficacy, safety and tolerability of an autologous T-cells expressing a chimeric antigen receptor (CAR) directed to B-Cell maturation antigen (BCMA) in patients with autoantibody-mediated myositis, including antisynthetase syndrome (ASyS) and dermatomyositis (DM).

Sponsor: Cartesian Therapeutics

Who Can Participate

Inclusion Criteria

Confirmed diagnosis of one of the following: Dermatomyositis (DM): Probability score ≥55% on the 2017 EULAR/ACR (European Alliance of Associations of Rheumatology/ American College of Rheumatology) criteria for classification of dermatomyositis (corresponding to diagnosis of 'probable or definite' DM). OR Antisynthetase Syndrome (ASyS): Diagnosis based on ACR/EULAR Classification Criteria (1)."
Participants must have dermatomyositis or antisynthetase syndrome with muscle and/or skin involvement.
Refractory or intolerance to standard therapy.
Stable background immunosuppressive therapy for ≥8 weeks.
Adequate hematologic, renal, hepatic, and pulmonary function (SpO₂ ≥92% on room air).
Informed consent, compliance with visits, contraception, and vaccinations required.

Exclusion Criteria

Isolated interstitial lung disease (ILD) without muscle or skin involvement
Severe irreversible muscle damage or advanced weakness (e.g., wheelchair-bound).
Interstitial lung disease (ILD) requiring oxygen, severe pulmonary impairment (FVC ≤45%, DLCO ≤40%), or pulmonary hypertension.
Other inflammatory myopathies (PM, IMNM, IBM, cancer- or drug-induced myositis, overlap myositis except Sjögren's).
Other severe neuromuscular, cardiac, pulmonary, or systemic autoimmune diseases requiring immunosuppression.
Significant uncontrolled chronic illnesses or psychiatric conditions interfering with participation.
Pregnancy or lactation.
Recent use of prohibited immunosuppressants/biologics or investigational agents (per washout periods).
Live vaccination within 4 weeks.
History of primary immunodeficiency, organ or bone marrow transplant.
Active or uncontrolled infections: HBV, HCV, HIV, tuberculosis, or recurrent/severe infections.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Austin?

Yes, this clinical trial (NCT07391605) has an active research site in Austin, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Antisynthetase Syndrome Treatment Options in Austin, TX

If you're searching for antisynthetase syndrome treatment options in Austin, TX, this clinical trial (NCT07391605) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Austin research site is actively enrolling participants for this clinical trial. You'll receive care from experienced antisynthetase syndrome specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all antisynthetase syndrome clinical trials near you to find additional studies recruiting in your area.

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