Cincinnati, OHNCT04221997Now EnrollingIRB Ready

Anxiety Disorders Clinical Trial in Cincinnati, OH

Access cutting-edge anxiety disorders treatment through this clinical trial at a research site in Cincinnati. Study-provided care at no cost to qualified participants.

Sponsored by University of Cincinnati

Quick Self-Assessment

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Expert Care in Cincinnati

Access anxiety disorders specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related anxiety disorders treatment provided free

Apply for This Cincinnati Location

Check if you qualify for this anxiety disorders clinical trial in Cincinnati, OH

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Cincinnati

    Convenient for OH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Cincinnati site if eligible
  4. 4Begin participation

About This Anxiety Disorders Study in Cincinnati

A Multicenter, acute, randomized, double-blind, placebo-controlled, flexible-dose trial with the treatment of sertraline.

Sponsor: University of Cincinnati

Who Can Participate

Inclusion Criteria

for Patients with Anxiety :
Written, informed assent and consent.
Patients, parent/guardian/LAR must be fluent in the English.
8-17 years of age, inclusive, at Visit 1, and who have a parent/guardian/LAR.
Patients must meet DSM-5 criteria for generalized, social and/or separation anxiety disorder, confirmed by the MINI-KID with no lifetime history of mania, OCD or significant history of trauma exposure.
PARS score ≥15 at Visits 1 and 2.
Caregiver who is willing to consent to be responsible for safety monitoring of the patient, provide information about the patient's condition, oversee the administration of the investigational product.
No clinically significant abnormalities on physical examination.
Negative pregnancy test at Visit 1 in females.
Sexually active patients must practice a reliable method of contraception (Section 15.0) that will continue for the duration of the study and within 30 days following the end of study participation.
Reliable methods of contraception are defined below; other forms of contraceptives (pharmacological and/or non-pharmacological) are not accepted.
surgical sterilization
oral contraceptives (e.g., estrogen-progestin combination or progestin)
transdermally-delivered contraceptives (e.g., Ortho-Evra), depot injections (e.g.,
Depo-Provera)
vaginal contraceptive ring (e.g., NuvaRing), contraceptive implants (e.g., Implanon, Norplant
II/Jadelle)
an intrauterine device or
diaphragm plus condom. Inclusion Criteria for Healthy Controls:
Written, informed assent and consent.
Patients, parent/guardian/LAR must be fluent in the English.
8 to 17 years of age, inclusive, at Visit 1, and who have a parent/guardian/LAR.
No history of any DSM-5 disorders (nicotine use disorder is permitted, history of adjustment disorder is permitted), confirmed by the MINI-KID.
Caregiver who is willing to consent to be responsible for safety monitoring of the patient, provide information about the patient.
No clinically significant abnormalities on physical examination. Negative pregnancy test at Screening in females.
Negative urine drug screen at Screening.
No first-degree relatives with an affective, anxiety or psychotic disorder.

Exclusion Criteria

for Patients with Anxiety Disorders and Healthy Comparison:
Subjects Co-occurring DSM-5 diagnosis mood (except persistent depressive disorder, unspecified depressive disorder or co- occurring anxiety disorders, provided that the primary diagnosis is generalized, social and/or separation anxiety disorder(s)), eating, bipolar, or psychotic disorders.
A history of treatment with SSRIs within 12 weeks of Visit 2 (Baseline) or current pharmacotherapy with CNS effects that require \>5 half-lives for discontinuation.
A history of major neurological or medical illness or head trauma with loss of consciousness for ≥5 minutes.
Lifetime history of mania, OCD, or significant history of trauma exposure.
History of hypersensitivity to sertraline.
Lifetime diagnosis of intellectual disability or history of IQ \<70.
History of alcohol/substance use disorder or any substance abuse within the past 6 months (nicotine dependence is permitted).
Current psychotherapy stable for \<2 months prior to Visit 2 (Baseline).
Females will not be eligible to participate if they are pregnant, breast feeding or lactating.
The subject lives \>100 miles from the University of Cincinnati or \>90 minutes from the CU site or is not able to attend the follow-up visits.
Patients who are unable to swallow capsules.
Is currently considered at risk of suicide in the opinion of the investigator, represents an inappropriate risk to the participant and/or could confound the interpretation of the study results.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Cincinnati?

Yes, this clinical trial (NCT04221997) has an active research site in Cincinnati, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Anxiety Disorders Treatment Options in Cincinnati, OH

If you're searching for anxiety disorders treatment options in Cincinnati, OH, this clinical trial (NCT04221997) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Cincinnati research site is actively enrolling participants for this clinical trial. You'll receive care from experienced anxiety disorders specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all anxiety disorders clinical trials near you to find additional studies recruiting in your area.

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