Cleveland, OHNCT06789809Now EnrollingIRB Ready

Aortic Aneurysm Clinical Trial in Cleveland, OH

Access cutting-edge aortic aneurysm treatment through this clinical trial at a research site in Cleveland. Study-provided care at no cost to qualified participants.

Sponsored by The Cleveland Clinic

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Expert Care in Cleveland

Access aortic aneurysm specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related aortic aneurysm treatment provided free

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Check if you qualify for this aortic aneurysm clinical trial in Cleveland, OH

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Cleveland

    Convenient for OH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Cleveland site if eligible
  4. 4Begin participation

About This Aortic Aneurysm Study in Cleveland

Aortic aneurysm patients benefit from exercise yet patients and physicians do not know a safe level. Cardiac MRI (CMR) is the most comprehensive imaging modality for phenotypic evaluation of patients with cardiac disease but it has not been used to study aneurysm patients. The purpose of this project is use exercise CMR to understand regional aortic function and quantify aortic elasticity in these populations while exercising. This project will correlate the exercise CMR data with the biomechanical properties of the patient's aortic tissue, including epiaortic ultrasound and TEE performed during aortic repair, and explanted aortic specimens subjected to ex vivo uniaxial tensile testing. Correlating this data with aortic response to exercise will allow us to understand how aortic size, in vivo circumferential strain values, ex vivo aortic efficiency and mechanical failure all relate to exercise physiology.

Sponsor: The Cleveland Clinic

Who Can Participate

Inclusion Criteria

Healthy controls for baseline comparison
Must be 18 years or older
No history of cardiovascular disease, neither hypertension, diabetes nor hypercholesterolemia
Aneurysm patients who have not yet been operated on but are currently being monitored
Must be 18 years or older
No history of operation for aortic aneurysm
Pre-operative aneurysm patients: imaged pre-operatively and 12 months
Patients admitted at the CCF cardiothoracic services for elective surgery due to aortic aneurysms
Must be 18 years or older

Exclusion Criteria

For all patients:
Contra-indication for MRI
Heart pacemaker/defibrillator.
Electronic/implanted stimulators or devices, including deep brain stimulator, vagus nerve stimulator, bladder stimulator, spine stimulator, neurostimulators; implanted electrodes or wires.
Cochlear implant or other ear implants.
Implanted drug pumps (insulin, narcotic/pain medications, drugs to treat spasticity).
Programmable shunt.
Aneurysm clips and coils.
Stents (not located in heart).
Filters (for example, blood clot filters).
Metal fragment in your body or eye (eg, BBs, bullets, shrapnel, metal pieces or shavings).
Congenital heart diseases such as patent ductus arteriosus, coarctation of aorta, ASD and VSD
Presence of A-V fistula or intracardiac shunts
Moderate or severe dysfunction in multiple valves
Patients with significant claustrophobia
Patients unable to pedal a supine bicycle
Those who require supplemental oxygen Specific Exclusion Criteria:
Healthy controls for baseline comparison
Excluded if using cardioprotective medication
Have a bicuspid aortic valve diagnosed using MRI
Pre-operative aneurysm patients: imaged pre-operatively and at 12 months a. Patients with traumatic aortic rupture

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Cleveland?

Yes, this clinical trial (NCT06789809) has an active research site in Cleveland, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Aortic Aneurysm Treatment Options in Cleveland, OH

If you're searching for aortic aneurysm treatment options in Cleveland, OH, this clinical trial (NCT06789809) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Cleveland research site is actively enrolling participants for this clinical trial. You'll receive care from experienced aortic aneurysm specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all aortic aneurysm clinical trials near you to find additional studies recruiting in your area.

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See all aortic aneurysm clinical trials recruiting in Cleveland — not just this study.

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Secure · Expert Care · Cleveland, OH