Columbia, SCNCT06832306Now EnrollingIRB Ready

ARDS (Moderate or Severe) Clinical Trial in Columbia, SC

Access cutting-edge ards (moderate or severe) treatment through this clinical trial at a research site in Columbia. Study-provided care at no cost to qualified participants.

Sponsored by Lungpacer Medical Inc.

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Expert Care in Columbia

Access ards (moderate or severe) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related ards (moderate or severe) treatment provided free

Apply for This Columbia Location

Check if you qualify for this ards (moderate or severe) clinical trial in Columbia, SC

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Columbia

    Convenient for SC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Columbia site if eligible
  4. 4Begin participation

About This ARDS (Moderate or Severe) Study in Columbia

Multi-center, randomized, controlled, open-label Phase 2 feasibility trial. Subjects on mechanical ventilation (MV) for acute hypoxemic respiratory failure (AHRF) with lung injury (including subjects who meet criteria for acute respiratory distress syndrome (ARDS)) will be randomized 2:1 to diaphragm neurostimulation-assisted ventilation (DNAV) using the AeroNova System plus lung-protective ventilation (Treatment) vs. lung-protective ventilation alone (Control).

Sponsor: Lungpacer Medical Inc.

Who Can Participate

Inclusion Criteria

Male or female, 18 years or older, and
Able to provide informed consent or have a legally authorized representative (LAR) / Substitute Decision Maker (SDM) who can provide consent, and
Have acute onset of new respiratory symptoms or dysfunction within the 2 weeks before onset of need for respiratory support, and
Have arterial hypoxemia defined by one of:
PaO2:FiO2 ratio ≤300 mm Hg on PEEP ≥5 cm H2O, or
In the absence of an available arterial blood gas, SpO2 ≤97% on FiO2 ≥0.5 and PEEP ≥5 cm H2O with reliable SpO2 trace for the 2 hours immediately preceding eligibility assessment (this correlates to an upper limit of SpO2:FiO2 ratio of 316%) or
Are receiving pulmonary vasodilators for acute hypoxemia, or
Are being ventilated in the prone position for acute hypoxemia, and
Have been mechanically ventilated for AHRF in the ICU for \<96 hours at the time of enrolment, and
Are expected to require invasive mechanical ventilation ≥48 hours after enrollment in the opinion of the treating clinician

Exclusion Criteria

Hypoxemia is primarily attributable to acute exacerbation of chronic obstructive pulmonary disease, status asthmaticus, cardiogenic pulmonary edema, or pulmonary embolism.
Underlying chronic parenchymal lung disease that may make recovery/extubation a challenge (e.g., COPD, pulmonary fibrosis).
Broncho-pleural fistula at the time of eligibility assessment.
Require extracorporeal membrane oxygenation.
Pre-existing neurological, neuromuscular or muscular disorder or known phrenic nerve injury that could affect the respiratory muscles.
BMI \>70 kg/m2.
Contraindications to left internal jugular vein or left subclavian vein catheterization (e.g., infection at the access site, known central venous stenosis, septic thrombophlebitis, left internal jugular ECMO cannula in situ, poor target vessels).
Patient expected to transition to fully palliative care within 72 hours of enrollment.
Chronic severe liver disease (e.g., Child-Pugh Score ≥10)
Treating clinician deems enrollment not clinically appropriate.
Currently enrolled in any other study of an investigational drug or device, which may affect the outcomes of the current study.
Any electrical device (implanted or external) that may be prone to interaction with or interference from the AeroNova System, including neurological pacing/stimulator devices and cardiac pacemakers and defibrillators.
Known or suspected to be pregnant or lactating.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Columbia?

Yes, this clinical trial (NCT06832306) has an active research site in Columbia, SC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

ARDS (Moderate or Severe) Treatment Options in Columbia, SC

If you're searching for ards (moderate or severe) treatment options in Columbia, SC, this clinical trial (NCT06832306) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Columbia research site is actively enrolling participants for this clinical trial. You'll receive care from experienced ards (moderate or severe) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all ards (moderate or severe) clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Columbia, SC