Baltimore, MDNCT03913117Now EnrollingIRB Ready

ASC-US Clinical Trial in Baltimore, MD

Access cutting-edge asc-us treatment through this phase 1 clinical trial at a research site in Baltimore. Study-provided care at no cost to qualified participants.

Sponsored by University of Alabama at Birmingham

Quick Self-Assessment

See if you qualify for this Baltimore location

Preparing your pre-screening questions…

Expert Care in Baltimore

Access asc-us specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related asc-us treatment provided free

Apply for This Baltimore Location

Check if you qualify for this asc-us clinical trial in Baltimore, MD

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Baltimore

    Convenient for MD residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Baltimore site if eligible
  4. 4Begin participation

About This ASC-US Study in Baltimore

Phase I clinical trial to assess safety of pNGVL4aCRTE6E7L2 DNA and TA-CIN protein vaccinations, and to seek the appropriate dose of the pNGVL4aCRTE6E7L2 DNA vaccine

Sponsor: University of Alabama at Birmingham

Who Can Participate

Inclusion Criteria

Patients with persistent (\>6 month period) ASC-US/LSIL determined by cervical cytology at study entry (ThinPrep with imaging)
Patients whose cytologic samples are persistent (\>6 month period) HPV16+ by Roche Cobas 4800, Roche Linear Array HPV Genotyping test or other FDA-approved HPV genotyping test at study entry. Co-infections with HPV types other than HPV16 are permissible for study entry.
Age ≥ 19 years
Baseline Eastern Cooperative Oncology Group
Patients must have adequate organ function at the time of enrollment as defined by the following parameters:
White blood cell count \> 3,000
Absolute lymphocyte number \> 500
Absolute neutrophil count \> 1,000
Platelets \> 90,000
Hemoglobulin \> 9
Total bilirubin \<3 X the institutional limit of normal
AST(SGOT)/ALT(SGPT) \<3 X the institutional limit of normal
Creatinine \< 2.5X the institutional limit of normal
Women of child-bearing potential must agree to use two forms of contraception (hormonal and barrier) prior to study entry and for 3 months after study completion.
Ability to understand and the willingness to sign a written informed consent document.
Subject is able to adhere to the study visit schedule and other protocol requirements.

Exclusion Criteria

Patients with ASC-US/LSIL determined by cervical cytology at study entry that are HPV16 negative.
Histologic evidence of CIN2+
Patients with a diagnosis of immunosuppression or prolonged, active use of immunosuppressive medications such as steroids.
Prior vaccination with any HPV antigen (prophylactic or therapeutic).
Patients who are receiving any other investigational agents within 28 days prior to the first dose.
Patients with an uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements.
Patients with a history of autoimmune disease such as multiple sclerosis, exclusive of a history of thyroiditis, psoriasis, Sjrogen's, or inflammatory bowel disease.
Patients with a history of allergic reactions attributed to compounds used in agent preparation.
Patients who are pregnant or breast feeding.
Patient with active or chronic infection of HIV, HCV, or HBV.
Patients who have had a prior LEEP or cervical conization procedure.
History of prior malignancy permitted if patient has been disease free for ≥ 5 years; however individuals with completely resected basal cell or squamous cell carcinoma of the skin within this interval may be enrolled.
Inability to understand or unwillingness to sign an informed consent document.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Baltimore?

Yes, this clinical trial (NCT03913117) has an active research site in Baltimore, MD that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

ASC-US Treatment Options in Baltimore, MD

If you're searching for asc-us treatment options in Baltimore, MD, this clinical trial (NCT03913117) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Baltimore research site is actively enrolling participants for this phase 1 clinical trial. You'll receive care from experienced asc-us specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all asc-us clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Baltimore, MD