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NCT07159308 · Children's Hospital of Philadelphia

Motivation for Daily Living Skills

What this study is about

The goal of this clinical trial is to enhance motivation to complete daily living skills among 16 to 25-year-old autistic teens and young adults.

View original scientific description

The goal of this clinical trial is to enhance motivation to complete daily living skills among 16 to 25-year-old autistic teens and young adults. Here are the main questions the trial aims to answer: Can this trial improve motivation to complete daily living skills for skills that people know how to do but struggle to do them consistently? Can this trial improve completion of the daily living skill that the participant identifies they want to do more often? Do people report feeling more empowered to complete the daily living skill they want to do more often? Are there any characteristics of a person that make them more or less likely to benefit from the treatment? Researchers will compare treatments that target different types of motivation: * One treatment focuses on internal motivation and explores what is important to someone and then connect that value back to their daily living skill goal. * A second treatment focuses on external motivation and will explore a person finding outside sources of motivation, like rewards. * A third treatment will use a combination of both methods. Autistic teens and young adults enrolled in this study will also be asked to choose someone in their life to be involved in the study with them. This person is called an "Important Person" (IP) and can be anyone close to them, like a family member, friend, roommate, partner, etc. The IP will be expected to support the teen/young adult throughout this treatment. Participants and their IPs will: * Complete five 'talk' therapy sessions that will last 60 to 90 minutes.

Who can participate

This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.

Inclusion criteria

  • for Autistic Teens and Young Adults:
  • Age 16-25 years
  • Participants reporting an autism diagnosis from a qualified provider (Psychiatrist, Psychologist, Developmental Pediatrician, Neurologist). When possible, diagnosis will be confirmed through the Children's Hospital of Philadelphia (CHOP) Electronic Health Record (EHR).
  • Must identify an important person who is able to communicate by understanding and speaking full sentences in English
  • Ability to communicate by understanding and using full sentences in English
  • Informed Consent
  • Be willing to have sessions audio- and video-recorded

Exclusion criteria

  • for Autistic Teens and Young Adults:
  • Diagnosis of Intellectual Disability
  • Participant is currently considered a suicide risk in the opinion of the Investigator or is currently demonstrating active suicidal or homicidal ideation or self-injurious behavior.
  • Current, comorbid psychiatric disorder with sufficiently intense symptoms in the opinion of the Investigator that these symptoms may confound treatment.
  • Changes to mental health treatment plan (ex. starting or ending therapy or psychotropic medications over the course of this intervention).
  • Participation in a prior trial of our intrinsic motivation condition Inclusion Criteria for Important Person:
  • Age 18 years or older
  • Must attend at least 15 minutes of each treatment session
  • Ability to communicate by understanding and using full sentences in English
  • Informed consent
  • Be willing to have sessions audio- and video-recorded Exclusion Criteria for Important Person: \- Is not willing to support the autistic teen/young adult with their daily living skill goal

Where

  • Philadelphia, Pennsylvania

Frequently asked questions

What is a clinical trial?

A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.

Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.

Will I be compensated?

Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.

Will I receive a placebo instead of treatment?

When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.

Can I leave a trial if I change my mind?

Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.

How long does a clinical trial last?

Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.

Data: ClinicalTrials.gov · synced Oct 2, 2025 · Source of record for eligibility and locations

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1 of 180 participants interested
1% interest

See if this study fits

A short prescreen based on this study's listed criteria. A coordinator confirms eligibility — this is not a medical assessment.

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Study locations

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RECRUITING

Philadelphia

Pennsylvania

Location available

Express your interest

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What participation can include

  • Study-related care provided by the research team
  • Close monitoring by medical professionals
  • Possible compensation for time and travel*
  • The option to withdraw at any time
  • Contributing to medical research that may help future patients

*Compensation varies by study. Confirm details with coordinator.

Typical next steps

  1. 1.Submit this form
  2. 2.Phone screening
  3. 3.In-person assessment if eligible
  4. 4.Begin participation

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Looking for Autism Spectrum Disorder (ASD) Treatment in Philadelphia?

Join others in Pennsylvania exploring innovative treatment options through clinical research

Autism Spectrum Disorder (ASD) Treatment Options in Philadelphia, Pennsylvania

If you're searching for Autism Spectrum Disorder (ASD) treatment in Philadelphia, participating in a clinical research study may provide access to innovative approaches under expert medical supervision. This study is actively recruiting participants in Philadelphia and surrounding areas.

Clinical trials offer participants the opportunity to receive cutting-edge treatments while contributing to medical research that may help future patients with Autism Spectrum Disorder (ASD). All study-related care is provided at no cost to participants.

Local Sites
1 locations in Pennsylvania
Now Enrolling
Up to 180 participants
Quick Start
Screening available now

Why Consider a Clinical Trial for Autism Spectrum Disorder (ASD)?

Potential Benefits

  • Access to new treatment approaches before public availability
  • Close monitoring by experienced medical professionals
  • Study-related care provided at no cost
  • Contribute to medical research for Autism Spectrum Disorder (ASD)

What to Expect

  • Initial screening to determine eligibility
  • Regular check-ups and monitoring visits
  • Possible compensation for time and travel
  • You can withdraw at any time

Frequently Asked Questions About This Autism Spectrum Disorder (ASD) Study

Important Clinical Trial Information

This information is provided for educational purposes and does not constitute medical advice. Clinical trial participation involves potential risks and benefits. Eligibility requirements apply and will be assessed during the screening process.

Study identifier: NCT07159308. For complete study details, visit ClinicalTrials.gov. Always consult with your healthcare provider before making decisions about your medical care or participating in clinical research.