Aurora, CONCT06582875Now EnrollingIRB Ready

Autosomal Dominant Polycystic Kidney Clinical Trial in Aurora, CO

Access cutting-edge autosomal dominant polycystic kidney treatment through this clinical trial at a research site in Aurora. Study-provided care at no cost to qualified participants.

Sponsored by University of Colorado, Denver

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Expert Care in Aurora

Access autosomal dominant polycystic kidney specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related autosomal dominant polycystic kidney treatment provided free

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Check if you qualify for this autosomal dominant polycystic kidney clinical trial in Aurora, CO

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Why Participate?

  • No-Cost Study Care

  • Local to Aurora

    Convenient for CO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Aurora site if eligible
  4. 4Begin participation

About This Autosomal Dominant Polycystic Kidney Study in Aurora

The proposed clinical trial aims to assess if a year of treatment with a glucagon-like peptide 1 receptor agonist, a medication approved for weight management that also improves the body's response to glucose and insulin, can slow kidney growth in adults with autosomal dominant polycystic kidney disease who are overweight or obese. The study will also evaluate changes in abdominal fat and kidney metabolism using cutting-edge images techniques. Blood and urine samples will provide further insight into biological changes that may be linked to the benefits of the intervention, while ensuring careful monitoring of safety and tolerability.

Sponsor: University of Colorado, Denver

Who Can Participate

Inclusion Criteria

18-65 years of age
ADPKD diagnosis based on the modified Pei-Ravine criteria
Body-mass index of ≥27 kg/m\^2
Estimated glomerular filtration rate ≥ 30 mL/min/1.73m\^2
Mayo Classification of C, D, or E, calculated from a previous kidney ultrasound or MRI performed within the last 12 months
Not currently participating in or planning to participate in any formal weight loss or physical activity program, or another interventional study
Ability to provide informed consent

Exclusion Criteria

Diabetes mellitus
Tolvaptan usage or plans to initiate tolvaptan
History of hospitalization or major surgery within the last 3 months
Uncontrolled hypertension (systolic blood pressure \> 160 or diastolic blood pressure \>100 mm Hg)
Pregnancy, lactation, or unwillingness to use adequate birth control
Regular use of prescription or over-the-counter medications that may affect weight, appetite, food intake, or energy metabolism
History of clinically diagnosed eating disorder including: anorexia nervosa, bulimia, binge eating disorder
Weight change of \>5% in the past 3 months for any reason except post-partum weight loss
Inability to cooperate with or clinical contraindication for MRI including: severe claustrophobia, implants, devices, or non-removable body piercings
Presence or personal history of malignant neoplasm within 5 years prior to the day of screening
Personal or family history of medullary thyroid carcinoma, thyroid nodule, or multiple endocrine neoplasia type 2
Prior history of pancreatitis
Weight ≥450 lb

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Aurora?

Yes, this clinical trial (NCT06582875) has an active research site in Aurora, CO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Autosomal Dominant Polycystic Kidney Treatment Options in Aurora, CO

If you're searching for autosomal dominant polycystic kidney treatment options in Aurora, CO, this clinical trial (NCT06582875) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Aurora research site is actively enrolling participants for this clinical trial. You'll receive care from experienced autosomal dominant polycystic kidney specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all autosomal dominant polycystic kidney clinical trials near you to find additional studies recruiting in your area.

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