Madera, CANCT05702645Now EnrollingIRB Ready

B Acute Lymphoblastic Leukemia Associated With Down Syndrome Clinical Trial in Madera, CA

Access cutting-edge b acute lymphoblastic leukemia associated with down syndrome treatment through this clinical trial at a research site in Madera. Study-provided care at no cost to qualified participants.

Sponsored by Children's Oncology Group

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IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related b acute lymphoblastic leukemia associated with down syndrome treatment provided free

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Why Participate?

  • No-Cost Study Care

  • Local to Madera

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Madera site if eligible
  4. 4Begin participation

About This B Acute Lymphoblastic Leukemia Associated With Down Syndrome Study in Madera

This study attempts to learn more about the health of persons with Down syndrome after treatment for acute leukemia. Children with Down syndrome are at increased risk for side effects during treatment for acute leukemia, but it is unclear of their risk for long-term effects of cancer treatment. By learning more about the factors that may contribute to chronic health conditions and long-term effects after treatment for leukemia in persons with Down syndrome, clinical practice guidelines for survivorship care can be developed to help improve their quality-of-life.

Sponsor: Children's Oncology Group

Who Can Participate

Inclusion Criteria

Patients age \>= 6 and \< 40 years at the time of enrollment
A diagnosis of Down syndrome is required, and may include any of the three recognized types: trisomy 21 resulting from chromosomal nondisjunction (most common), translocation (the patient has 46 chromosomes, but all or part of an additional copy of chromosome 21 is attached to another chromosome), or mosaicism (trisomy 21 that is present in only a fraction of cells)
All patients must be DS-AL survivors (acute lymphoblastic leukemia \[ALL\] or acute myeloid leukemia \[AML\])
Note 1: Myeloid leukemia of Down syndrome (ML-DS) is included in the AML category above. Per the World Health Organization (WHO) definition of ML-DS, this diagnosis encompasses both myelodysplastic syndrome (MDS) and overt AML. Also, note that survivors of relapsed disease are eligible, so long as the patient otherwise meets eligibility criteria, i.e., treatment for relapse was completed at least 36 calendar months prior to enrollment and did not include stem cell transplant
Note 2: A diagnosis of transient abnormal myelopoiesis (TAM), also known as transient myeloproliferative disease (TMD), is not alone sufficient for inclusion in this study
Patients must have been treated for ALL or AML
Note: History of COG therapeutic trial participation is not required. As a reminder ML-DS would be included under the AML category here above
All cancer treatment (oral or intravenous) must have been completed at least 36 calendar months prior to enrollment
Patients must have a life expectancy of \> 1 year
Patient and parent of subject must be either English or Spanish speaking. At least one parent or guardian must be able to read and write in English or Spanish
Note: Parents or guardians are responsible for completing all questionnaires, even in the case of subjects that are \>= 18 years old
All patients and/or their parents or legal guardians must sign a written informed consent
All institutional, Food and Drug Administration (FDA), and National Cancer Institute (NCI) requirements for human studies must be met

Exclusion Criteria

Patients with history of hematopoietic stem cell transplant (HSCT) are excluded
Note: Patients with previous chimeric antigen receptor T-cell (CAR T-cell) therapy, and other cellular cancer therapies can participate, as long as all other eligibility criteria are satisfied
Patients with a history of cancers prior to their ALL or AML diagnosis are excluded. Patients that developed a subsequent malignant neoplasm following their ALL or AML diagnosis are also excluded
Note: Prior history of transient abnormal myelopoiesis is allowed, but is not sufficient for eligibility
Patients whose parents or guardians are unable to complete the required forms are excluded

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Madera?

Yes, this clinical trial (NCT05702645) has an active research site in Madera, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

B Acute Lymphoblastic Leukemia Associated With Down Syndrome Treatment Options in Madera, CA

If you're searching for b acute lymphoblastic leukemia associated with down syndrome treatment options in Madera, CA, this clinical trial (NCT05702645) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Madera research site is actively enrolling participants for this clinical trial. You'll receive care from experienced b acute lymphoblastic leukemia associated with down syndrome specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all b acute lymphoblastic leukemia associated with down syndrome clinical trials near you to find additional studies recruiting in your area.

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