Phoenix, AZNCT06623201Now EnrollingIRB Ready

Basal Cell Carcinoma (BCC) Clinical Trial in Phoenix, AZ

Access cutting-edge basal cell carcinoma (bcc) treatment through this phase 1 clinical trial at a research site in Phoenix. Study-provided care at no cost to qualified participants.

Sponsored by Nathalie Zeitouni

Quick Self-Assessment

See if you qualify for this Phoenix location

Preparing your pre-screening questions…

Expert Care in Phoenix

Access basal cell carcinoma (bcc) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related basal cell carcinoma (bcc) treatment provided free

Apply for This Phoenix Location

Check if you qualify for this basal cell carcinoma (bcc) clinical trial in Phoenix, AZ

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Phoenix

    Convenient for AZ residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Phoenix site if eligible
  4. 4Begin participation

About This Basal Cell Carcinoma (BCC) Study in Phoenix

This research study is testing combination Blue-light photodynamic therapy and Sonidegib as a possible treatment for people with multiple basal cell carcinoma lesions. Basal cell carcinoma lesions are typically treated by freezing the lesion or surgically removing the lesion. These types of treatment can cause scarring. Photodynamic therapy uses light along with a drug applied to the skin to kill the cancer cells and cause them to break apart. The light used can cause the skin to feel warm, but does not cause scarring.

Sponsor: Nathalie Zeitouni

Who Can Participate

Inclusion Criteria

Patients will be included in the study based on the following criteria:
Male or females, at least 18 years of age.
Diagnosis of BCC with at least 3 nodular lesions that measure 0.5 cm to 5 cm in diameter, located on the head and neck, trunk or extremities.
Diagnosis must be confirmed clinically at baseline with 1-3 lesions having been biopsied no sooner than 2 weeks prior to treatment.
Patients who may have high burden of disease (i.e., large lesions), who are non-surgical candidates or who refuse surgery.
Non-surgical candidates, who may be able to undergo resection of selected single, individual lesion, but may not tolerate extensive surgery, may have many co morbidities, may be prone to complications.
Patients in whom surgery or radiation therapy may be impractical.
Primary lesions may be acceptable for enrollment.
Within normal limit hematopoietic capacity, hepatic and renal function. Values outside those limits may be allowed at the discretion of the PI, if they are determined as not clinically significant.
Evidence of a personally signed and dated informed consent document indicating that the subject (or legally acceptable representative) has been informed of all pertinent aspects of the trial.
Ability to understand and the willingness to sign a written informed consent document in English. Exclusion Criteria Patients will be excluded from the study based on the following criteria:
Sexually active women of childbearing (WOCBP)\
who are unwilling to practice highly effective contraception prior to the initial dose/start of the first treatment, during the study, and for 20 months after the final dose of treatment. Highly effective contraceptive measures include:
Stable use of combined (estrogen and progestogen containing) hormonal contraception (oral, intravaginal, transdermal) or progestogen-only hormonal contraception (oral, injectable, implantable) associated with inhibition of ovulation
Intrauterine device (IUD); intrauterine hormone-releasing system
Bilateral tubal ligation;
Vasectomized partner (provided that the vasectomized partner is the sole sexual partner of the WOCBP study subject);
and/or sexual abstinence.
Childbearing potential refers to a female who has reached menarche, has not had a surgical sterilization procedure (such as a hysterectomy or bilateral oophorectomy), and is not postmenopausal. Menopause is defined as 12 consecutive months of amenorrhea without other biological causes. Furthermore, for females under 55 years old, a serum follicle-stimulating hormone level greater than 40 mIU/mL must be documented to confirm menopause.
Sexually active males who are unwilling to use a condom with female partners of childbearing potential, during the study, and for at least 8 months after the last dose of treatment.
Subjects who plan on donating blood or blood products during the study and for at least 20 months after the last dose of treatment. Male subjects must agree not to donate sperm during the study and for at least 8 months after the last dose of treatment.
Target lesions of basal cell carcinomas of aggressive subtypes (infiltrative, morpheaform, micronodular).
Any BCC that may require Mohs surgery for definitive control as a target lesion.
Subjects with porphyria's or known hypersensitivity to porphyrins.
Subjects with known photosensitivity diseases.
Subjects previously treated with a systemic photosensitizer within 4 months of screening date.
Subjects who desire to get pregnant a female of childbearing potential within the next 1.5 years.
Uncontrolled concomitant illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements.
Life expectancy less than one year.
Inability or unwillingness to swallow capsules.
Have a history of alcohol of substance abuse, unless in full remission for greater than 6 months prior to the screening visit (Day 0) when the consent form is signed.
Having used any of the following treatment within 6 months before the baseline visit:
hedgehog pathway inhibitor, biologics, or chemotherapy
topical chemotherapy agents including Imiquimod, fluorouracil,) to the selected treatment lesion sites within 3 weeks.
Currently undergoing treatment with photodynamic therapy within 3 weeks before baseline visit.
Subjects who have received any type of solid organ transplant.
Subjects taking immunosuppressive medications at the screening visit that interact with Sonidegib at the screening visit unless approved by the investigator..
Participation in other study using an investigational or experimental therapy or procedure within 4 weeks or 5 half-lives (whichever is longer) before the screening visit and/or during study participation. Subjects cannot participate in studies of other investigational or experimental therapies or procedures at any time during their participation in this study.
Other severe acute or chronic medical or psychiatric condition or laboratory abnormality that may increase the risk associated with study participation or investigational product administration or may interfere with the interpretation of study results and, in the judgment of the investigator, would make the subject inappropriate for entry into this study.
Subjects unable or unwilling to comply with the study visit schedule and requirements of the study.
Subjects unable to speak and read the English language.
A subject who, in the opinion of the sponsor-investigator will be uncooperative or unable to comply with study procedures.
A subject who, in the opinion of the sponsor-investigator will be uncooperative or unable to comply with study procedures.

Exclusion Criteria

Patients will be excluded from the study based on the following criteria:
Sexually active women of childbearing (WOCBP)\
who are unwilling to practice highly effective contraception prior to the initial dose/start of the first treatment, during the study, and for 20 months after the final dose of treatment. Highly effective contraceptive measures include:
Stable use of combined (estrogen and progestogen containing) hormonal contraception (oral, intravaginal, transdermal) or progestogen-only hormonal contraception (oral, injectable, implantable) associated with inhibition of ovulation
Intrauterine device (IUD); intrauterine hormone-releasing system
Bilateral tubal ligation;
Vasectomized partner (provided that the vasectomized partner is the sole sexual partner of the WOCBP study subject);
and/or sexual abstinence.
Childbearing potential refers to a female who has reached menarche, has not had a surgical sterilization procedure (such as a hysterectomy or bilateral oophorectomy), and is not postmenopausal. Menopause is defined as 12 consecutive months of amenorrhea without other biological causes. Furthermore, for females under 55 years old, a serum follicle-stimulating hormone level greater than 40 mIU/mL must be documented to confirm menopause.
Sexually active males who are unwilling to use a condom with female partners of childbearing potential, during the study, and for at least 8 months after the last dose of treatment.
Subjects who plan on donating blood or blood products during the study and for at least 20 months after the last dose of treatment. Male subjects must agree not to donate sperm during the study and for at least 8 months after the last dose of treatment.
Target lesions of basal cell carcinomas of aggressive subtypes (infiltrative, morpheaform, micronodular).
Any BCC that may require Mohs surgery for definitive control as a target lesion.
Subjects with porphyria's or known hypersensitivity to porphyrins.
Subjects with known photosensitivity diseases.
Subjects previously treated with a systemic photosensitizer within 4 months of screening date.
Subjects who desire to get pregnant a female of childbearing potential within the next 1.5 years.
Uncontrolled concomitant illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements.
Life expectancy less than one year.
Inability or unwillingness to swallow capsules.
Have a history of alcohol of substance abuse, unless in full remission for greater than 6 months prior to the screening visit (Day 0) when the consent form is signed.
Having used any of the following treatment within 6 months before the baseline visit:
hedgehog pathway inhibitor, biologics, or chemotherapy
topical chemotherapy agents including Imiquimod, fluorouracil,) to the selected treatment lesion sites within 3 weeks.
Currently undergoing treatment with photodynamic therapy within 3 weeks before baseline visit.
Subjects who have received any type of solid organ transplant.
Subjects taking immunosuppressive medications at the screening visit that interact with Sonidegib at the screening visit unless approved by the investigator..
Participation in other study using an investigational or experimental therapy or procedure within 4 weeks or 5 half-lives (whichever is longer) before the screening visit and/or during study participation. Subjects cannot participate in studies of other investigational or experimental therapies or procedures at any time during their participation in this study.
Other severe acute or chronic medical or psychiatric condition or laboratory abnormality that may increase the risk associated with study participation or investigational product administration or may interfere with the interpretation of study results and, in the judgment of the investigator, would make the subject inappropriate for entry into this study.
Subjects unable or unwilling to comply with the study visit schedule and requirements of the study.
Subjects unable to speak and read the English language.
A subject who, in the opinion of the sponsor-investigator will be uncooperative or unable to comply with study procedures.
A subject who, in the opinion of the sponsor-investigator will be uncooperative or unable to comply with study procedures.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Phoenix?

Yes, this clinical trial (NCT06623201) has an active research site in Phoenix, AZ that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Basal Cell Carcinoma (BCC) Treatment Options in Phoenix, AZ

If you're searching for basal cell carcinoma (bcc) treatment options in Phoenix, AZ, this clinical trial (NCT06623201) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Phoenix research site is actively enrolling participants for this phase 1 clinical trial. You'll receive care from experienced basal cell carcinoma (bcc) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all basal cell carcinoma (bcc) clinical trials near you to find additional studies recruiting in your area.

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