NCT07398443 · Brown University
Using Novel Behavioral Economic Measures to Characterize Dual Marijuana and Tobacco Use in Young Adults
(MATEY)
What this study is about
The multi session experimental study aims to determine dual use patterns of marijuana and tobacco by assessing the impact of price and availability of marijuana and tobacco using a cross price elasticity of demand task. The study will recruit 120 non-treatment seeking emerging young adults (18-25 years) who smoke marijuana and tobacco.
View original scientific description
The multi session experimental study aims to determine dual use patterns of marijuana and tobacco by assessing the impact of price and availability of marijuana and tobacco using a cross price elasticity of demand task. The study will recruit 120 non-treatment seeking emerging young adults (18-25 years) who smoke marijuana and tobacco.
Interventions
BEHAVIORAL
Cue Reactivity
Participants will be exposed to neutral followed by cannabis or tobacco cues in a fixed sequence while they answer questions about their subjective state. The cues will include everyday items (e.g., eraser) and cannabis-related items (e.g., lighter).
Primary outcome measures
Change in self-reported cannabis craving
Time frame: Up to 40 days post-baseline session
This study utilizes a structured cannabis cue exposure paradigm. During cue exposure, participants rate subjective craving on a scale from 0, "Not at all," to 10, "Extremely." Cannabis craving will be assessed following neutral cue exposure and then cannabis cue exposure. The primary outcome will be change in cannabis craving.
Change in self-reported tobacco craving
Time frame: Up to 40 days post-baseline session
This study utilizes a structured tobacco cue exposure paradigm. During cue exposure, participants rate subjective craving on a scale from 0, "Not at all," to 10, "Extremely." Tobacco craving will be assessed following neutral cue exposure and then tobacco cue exposure. The primary outcome will be change in tobacco craving.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Males/females who are 18 to 25 years of age
- Young adults who currently smoke commercial tobacco cigarettes (≥1x weekly in the past 30 days and for the past six months)
- Young adults who currently smoke marijuana (≥4 times in past 30 days and at least weekly on average for the last six months)
- Participants must report purchasing their own tobacco and marijuana at least once in the past 6 months
- Participants must speak, comprehend, and read English.
Exclusion criteria
- Intention to quit marijuana or tobacco use in the next 30 days
- Self-reported illicit drug or heavy episodic alcohol use on \>20 days in the past month (excluding marijuana)
- Individuals who are pregnant or breastfeeding
- Positive saliva test for recent THC use
- Breath alcohol level above 0 at any session.
- Participants who exclusively roll their own tobacco cigarettes
Where
- Providence, Rhode Island
Collaborators
National Institutes of Health (NIH), National Cancer Institute (NCI)
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Mar 4, 2026 · Source of record for eligibility and locations