Is NCT07460947 recruiting in Belmont, MA?

Yes, NCT07460947 is currently recruiting participants at its Belmont, MA location. This borderline personality disorder (bpd) clinical trial is actively enrolling qualified participants.

Is participation in this Belmont clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Borderline Personality Disorder (BPD) Clinical Trial in Belmont, MA

Q: How do I join the borderline personality disorder (bpd) clinical trial in Belmont?

To join this clinical trial in Belmont, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

About This Borderline Personality Disorder (BPD) Study in Belmont

This study tests a new treatment for people with borderline personality disorder (BPD). The treatment combines a medication called D-cycloserine with one day of transcranial magnetic stimulation (TMS). The main questions it aims to answer are: * How many participants complete the treatment? * How do participants feel about the treatment? * Does the treatment have neurophysiological changes on participants? * Does the treatment improve BPD symptoms? * Do the benefits last over time? Participants will be asked to: * Come to the clinic for interviews and testing * Complete weekly questionnaires for 4 weeks before the treatment day * Take D-cycloserine the night before treatment * Attend one treatment day at the clinic. On that day, they may receive up to 20 short TMS sessions (each lasting 3 minutes and separated by 30 minutes). This visit may last up to 12 hours. * Complete weekly questionnaires for 6 weeks after the treatment day.

Sponsor: Mclean Hospital

Who Can Participate

Inclusion Criteria

Adult (18+) of any gender

Meets DSM-5 criteria for BPD, per assessment with the Structured Clinic Interview for DSM-5 Personality Disorders (SCID-5-PD), BPD Module

Moderate to severe SI during the two weeks prior to screening, as indexed by a score of 9 or higher on the Modified Scale for Suicide Ideation - Self Report (Clum \& Yang, 1995)

Exclusion Criteria

Current manic or hypomanic symptoms, as assessed by the Diagnostic Assessment Research Tool (DART) screener and diagnostic modules, where relevant.

Current clinically significant psychotic symptoms not better accounted for by BPD, as assessed by the DART psychotic symptoms screener.

Current alcohol or substance use disorder, that in the opinion of a study PIs, is of sufficient severity to impede engagement in treatment or is associated with significant risk of medical withdrawal, as assessed by the DART.

Medical documentation or self-report of current anorexia nervosa, bulimia nervosa, or eating disorder not otherwise specified - atypical anorexia nervosa or atypical bulimia nervosa, that is in the opinion of a study PIs is of sufficient severity to be associated with significant medical risks

Acute suicide risk, sufficient to require immediate hospitalization;

history of traumatic brain injury (TBI) or concussion involving loss of consciousness or amnesia for ≥24 hours;

any significant neurological disorder likely to be associated with increased intracranial pressure or cognitive impairment (e.g., epilepsy; Parkinson's disease);

diagnosed neurodevelopmental disorder (e.g., autism, downs syndrome; Ehlers-Danlos Syndrome) other than attention-deficit hyperactivity disorder (ADHD) or dyslexia

current diagnosis of delirium or dementia;

cognitive disorder secondary to a general medical condition

Pregnant and breastfeeding people are excluded in line with the studies our protocol is based upon using DCS and aTMS. Assessment of pregnancy will be completed during the 1-week prior to the administration of DCS (i.e., taken the night before TMS treatment), where relevant and according to MGB IRB policy.

Participants with contraindications to TMS (e.g., metal in head or neck area), or at increased risk for adverse events (e.g., seizure history or markedly heightened risk factors for seizures, serious medical problems, implanted devices) will be excluded.

Participants with a known allergy to DCS will be excluded from the study.

No patients with involuntary hospitalization status will be recruited for the study.

No individuals who are not proficient in English will be recruited for the study

Subject does not have a PCP

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Belmont?

Yes, this clinical trial (NCT07460947) has an active research site in Belmont, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Borderline Personality Disorder (BPD) Treatment Options in Belmont, MA

If you're searching for borderline personality disorder (bpd) treatment options in Belmont, MA, this clinical trial (NCT07460947) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Belmont research site is actively enrolling participants for this clinical trial. You'll receive care from experienced borderline personality disorder (bpd) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all borderline personality disorder (bpd) clinical trials near you to find additional studies recruiting in your area.

Borderline Personality Disorder (BPD) Clinical Trial in Belmont, MA

Expert Care in Belmont

IRB Approved

No-Cost Care

Apply for This Belmont Location

Why Participate?

Simple Process