Is NCT07356284 recruiting in Toledo, OH?

Yes, NCT07356284 is currently recruiting participants at its Toledo, OH location. This brain stroke clinical trial is actively enrolling qualified participants.

How do I join the brain stroke clinical trial in Toledo?

To join this clinical trial in Toledo, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

Is participation in this Toledo clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Brain Stroke Clinical Trial in Toledo, OH

About This Brain Stroke Study in Toledo

The study objective is to establish the safety and efficacy of endovascular adjunct stenting for patients undergoing mechanical thrombectomy (MT) that are found to have residual stenosis (70-99%) following attempted clot retrieval with either aspiration catheters or stent retrievers, per device instructions for use and device labeling.

Sponsor: ProMedica Health System

Who Can Participate

Inclusion Criteria

18 to 80 years of age

Presenting with symptoms consistent with AIS

Imaging evidence of an anterior occlusion of the Internal Carotid Artery (ICA) or Middle Cerebral Artery Main Stem (MCA M1), or proximal M2 segment AND residual 70-99% stenosis of the index artery following attempted clot retrieval with either aspiration catheters or stent retrievers, per device instructions for use and device labeling

Ability to randomize within 24 hours of stroke onset.

Pre-stroke mRS score 0-2

Ability to obtain signed informed consent.

ASPECTS Score ≥ 6 by non-contrast CT scan

Score-ICAD score of ≥11 points at screening and/or persistent stenotic occlusion of ≥70% after MT

If indicated, thrombolytic therapy shall be initiated per the institution's usual care and the most recent version of the AHA/ASA Guidelines. Subjects eligible for IV thrombolysis should receive it without delay.

For subjects presenting \>6 hours from stroke onset, infarct core volume \<50 cc quantified by CTP

Exclusion Criteria

Females who are pregnant, or those of child-bearing potential with positive urine or serum beta Human Chorionic Gonadotropin (HCG) test

Known severe allergy (more than a rash) to contrast media uncontrolled by medications.

CT evidence of the following conditions:

Midline shift or herniation

Evidence of intracranial hemorrhage

Mass effect with effacement of the ventricles

Acute bilateral strokes

Contraindication to antiplatelet (aspirin, clopidogrel, ticagrelor, cangrelor) or contrast agents

Intracranial tumors other than small meningioma, that do not require surgery for at least one year post randomization. Small meningioma is defined as a lesion measuring ≤20mm in maximum diameter or ≤4cm3 in volume, with no associated mass effect, peritumoral edema, or progressive neurological symptoms

Known hemorrhagic diathesis, coagulation factor deficiency, or on anticoagulant therapy with an International Normalized Ratio (INR) of \>3.0 or Partial Thromboplastin Time (PTT) \>3 times of normal

Baseline platelet count \<80,000 per microliter (µl)

Life expectancy less than one year prior to stroke onset

Participation in another randomized clinical trial that could confound the evaluation of the study outcomes.

Any other condition (in the opinion of the site investigator) that precludes an endovascular procedure or poses a significant hazard to the patient if an endovascular procedure was performed

New diagnosis of atrial fibrillation or a history of atrial fibrillation

Suspected device-induced vasospasm defined as smooth transient narrowing of the target vessel

Vessel dissection including any of the following: presence of dissection flap, false lumen, contrast stagnation in the vessel wall, and/or improving stenosis \-

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Toledo?

Yes, this clinical trial (NCT07356284) has an active research site in Toledo, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Brain Stroke Treatment Options in Toledo, OH

If you're searching for brain stroke treatment options in Toledo, OH, this clinical trial (NCT07356284) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Toledo research site is actively enrolling participants for this phase 3 clinical trial. You'll receive care from experienced brain stroke specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all brain stroke clinical trials near you to find additional studies recruiting in your area.

Brain Stroke Clinical Trial in Toledo, OH

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