Is NCT06268665 recruiting in Sacramento, CA?

Yes, NCT06268665 is currently recruiting participants at its Sacramento, CA location. This breast cancer clinical trial is actively enrolling qualified participants.

How do I join the breast cancer clinical trial in Sacramento?

To join this clinical trial in Sacramento, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

Is participation in this Sacramento clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Breast Cancer Clinical Trial in Sacramento, CA

About This Breast Cancer Study in Sacramento

This is a single institution phase II randomized study evaluating the potential benefits of a supplement, tart cherry juice at high- versus low-doses, to prevent taxane induced peripheral neuropathy in breast and ovarian cancer patients undergoing paclitaxel chemotherapy. Eligible participants enrolled onto the study will be block randomized in a 1:1 allocation to either the tart cherry juice high-dose group (Arm 1) or the tart cherry juice low-dose group (Arm 2).

Sponsor: University of California, Davis

Who Can Participate

Inclusion Criteria

Histologically confirmed invasive breast or ovarian cancer (Stage I, II, III, or IV) as per AJCC 8th Edition, 2018 Staging Criteria.

Must be planning to receive paclitaxel weekly for 12 weeks (12 weeks total) as part of neoadjuvant, adjuvant, or metastatic cancer treatment.

Concurrent biologic therapy (e.g., trastuzumab and pertuzumab) is allowed.

Currently receiving hormone therapy, bisphosphonates, denosumab or LHRH-agonists is allowed.

Concurrent use of immune checkpoint inhibitor therapy is allowed.

(Neo)adjuvant chemotherapy with doxorubicin and cyclophosphamide is allowed.

Concurrent use of carboplatin with weekly paclitaxel in the study is allowed.

May participate concurrently in other cancer trials.

Must be able to complete questionnaires in English or Spanish.

Age ≥ 18 years old at the time of consent.

ECOG performance status of 0 - 1 (Karnofsky scale ≥ 70%, see Appendix).

Ability to understand and the willingness to sign a written informed consent document.

Individuals of child-bearing potential must agree to use birth control (e.g., hormonal or barrier method; abstinence, an intrauterine device) prior - to study entry, for the duration of study participation (including dose interruptions), and for 3 months after the last dose of tart cherry juice supplement; or be surgically sterilized (e.g., hysterectomy or tubal ligation).

Patients with known human immunodeficiency virus (HIV) are allowed in the study, but HIV-positive patients must have:

A stable regimen of highly active anti-retroviral therapy (HAART)

No requirement for concurrent antibiotics or antifungal agents for the prevention of opportunistic infections

A CD4 count above 250 cells/µL and an undetectable HIV viral load on standard PCR-based tests within the last year.

Stated willingness to not drink any additional tart cherry or any cherry juice while on the study.

Ability and willingness to adhere to the study visit schedule and other protocol requirements

Exclusion Criteria

Have received any prior therapy with taxanes, vinca alkaloids, eribulin, ixabepilone, or platinum. Doxorubicin is allowed (≥ 2 week washout period required).

Active or history of peripheral neuropathy, or any chronic diseases associated with peripheral neuropathy such as diabetes mellitus, alcohol use disorder, or systemic lupus erythematosus.

Currently taking anticoagulant medication.

Currently taking Vitamin E, glutamine, alpha lipoic acid, gabapentin, nortriptyline, amitriptyline or duloxetine. If a patient is taking any of these supplements/medications, they must agree to stop at the time of registration. Multivitamins containing Vitamin E are allowed, however Vitamin E \> 1,000 international units (IU) must be discontinued at the time of registration.

Patients may not use cold therapy gloves for chemotherapy induced neuropathy.

Known allergy to cherries.

Inability to swallow liquid.

Pregnant or breastfeeding individuals (lactating individuals must agree not to breast feed while taking study juice supplementation).

Any condition that would prohibit the understanding or rendering of informed consent.

Any condition that in the opinion of the investigator would interfere with safety or compliance while on trial.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Sacramento?

Yes, this clinical trial (NCT06268665) has an active research site in Sacramento, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Breast Cancer Treatment Options in Sacramento, CA

If you're searching for breast cancer treatment options in Sacramento, CA, this clinical trial (NCT06268665) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Sacramento research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced breast cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all breast cancer clinical trials near you to find additional studies recruiting in your area.

Breast Cancer Clinical Trial in Sacramento, CA

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