NCT05721976 · University of Miami Sylvester Comprehensive Cancer Center
With Love, Grandma ("Con Cariño, Abuelita") Pilot Study
What this study is about
The purpose of this study is to assess the feasibility, acceptability, and preliminary effects of a digital (web and mobile-phone-based) program to improve lifestyle behaviors (physical activity, dietary intake) among Hispanic female cancer survivors and adult daughters.
View original scientific description
The purpose of this study is to assess the feasibility, acceptability, and preliminary effects of a digital (web and mobile-phone-based) program to improve lifestyle behaviors (physical activity, dietary intake) among Hispanic female cancer survivors and adult daughters.
Interventions
BEHAVIORAL
With Love, Grandma ("Con Cariño, Abuelita")
Cancer survivor-Daughter dyads will log in to a secured website to access intervention content over a period of 10-12 weeks. The intervention will be delivered primarily through smartphones and will include 8 modules with didactic content on healthy lifestyle behaviors for cancer prevention and control, family behavior change content for setting weekly goals and self-monitoring health behaviors, and family communication and positive parenting/grandparenting content, all of which were developed in accordance with participant feedback based on formative intervention development work. In addition, and to increase participant compliance/reduce attrition often observed in digital health interventions, human support ("supportive accountability") will be provided. Specifically, each family will be assigned a "coach" who will use video conferencing software to engage in weekly 15-30 minute sessions regarding the family's progress throughout the intervention period.
Primary outcome measures
Percent of survivor-daughter dyads retained at post-intervention (feasibility)
Time frame: Up to 3 months
Calculated by percent of enrolled survivor-daughter dyads who completed post-intervention measures
Percent of modules completed by survivor-daughter dyads (acceptability)
Time frame: Up to 3 months
Calculated as number of modules completed (of 8 total modules) by survivors and daughters
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Grandmother
- Self-identifies as Hispanic
- Diagnosis of breast cancer (stages I-III), endometrial or ovarian cancer (stages I-II)
- Completed active treatment (i.e., surgery, chemotherapy, and/or radiation)
- Body Mass Index (BMI) ≥ 25 (overweight range)
- Engages in \<150 minutes/week of moderate physical activity
- English or Spanish speaking
- Owns a mobile device with internet access (e.g., smartphone, tablet)
- Lives in South Florida Daughter of Cancer Survivor Inclusion Criteria:
- Adult daughter of the identified cancer survivor (21 years of age or older)
- Has at least 1 living child ages ≤16 years old
- Body Mass Index (BMI) ≥ 25 (overweight range) OR engages in \<150 minutes/week of moderate physical activity
- English or Spanish speaking
- Owns a mobile device with internet access (e.g., smartphone, tablet)
- Lives in South Florida Daughter of Cancer Survivor
Exclusion criteria
- Has been diagnosed with distant metastatic cancer
- Has not completed active treatment (i.e., surgery, chemotherapy, and/or radiation)
- Has uncontrolled schizophrenia or bipolar disorder
- Has a preexisting medical condition that precludes unsupervised physical activity (e.g., severe orthopedic conditions,wheelchair bound). Cancer Survivor Exclusion Criteria:
- Has uncontrolled schizophrenia or bipolar disorder
- Has a preexisting medical condition that precludes unsupervised physical activity (e.g., severe orthopedic conditions, wheelchair bound)
Where
- Miami, Florida
Collaborators
The V Foundation for Cancer Research
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Feb 25, 2026 · Source of record for eligibility and locations