NCT01742143 · Memorial Sloan Kettering Cancer Center
Impact of ICCAN on Cancer Treatment Completion and Quality of Life
What this study is about
The purpose of this study is to see if the ICCAN program is working, and to compare the ICCAN program to the standard hospital services provided in New York City hospitals, like meeting with a Social Worker or a Patient Navigator (a person who provides personal hospital guidance).
View original scientific description
The purpose of this study is to see if the ICCAN program is working, and to compare the ICCAN program to the standard hospital services provided in New York City hospitals, like meeting with a Social Worker or a Patient Navigator (a person who provides personal hospital guidance).
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Patient is eligible if he/she is
- fluent in English, Spanish, or Mandarin
- between the ages of 21-80 years old
- cancer patients currently receiving chemotherapy (started within the past month) and/or radiation therapy (started within the past week), or
- scheduled to begin chemotherapy and/or radiation therapy within the next 2 months (excluding surgery only patients)
- planning on remaining in the area for at least 1 year Clinician is eligible if he/she:
- Has an MD or DO degree
- Is the treating physician providing care to a patient enrolled to the study ICCAN-IO Phase 1: Refinement, participant is eligible if he/she per EMR or self-report:
- Is 18 - 85 years of age
- Has unresectable locally advanced, locally recurrent unresectable, metastatic, or high risk/early stage TNBC or stage I-IV lung cancer
- Eligible for FDA approved immunotherapy in the NYC metropolitan area (per self-report or per MSK patient EMR records).
- Is treated in the NY metropolitan area
- Self-identifies as Black or Hispanic, and/or is low-SES (low SES will be defined as household income \< 200% of federal poverty level)
- Has English or Spanish proficiency
- Agrees to be audio-recorded ICCAN-IO Phase 2: Pilot RCT, participant is eligible if he/she per EMR or self-report:
- Is 18 - 85 years of age
- Has stage II-III TNBC
- Treated at MSK Manhattan or OneMSK regional sites
- Self identifies as Black or Hispanic, and/or is low SES (low SES will be defined as household income \< 200% of federal poverty level)
- Has English or Spanish proficiency
- Agrees to be audio-recorded ICCAN-IO process evaluation study team participants only:
- Staff member who serves as an Access Facilitator
- Agrees to be audio-recorded CCAN-GBM
- Over the age of 18 (per EMR)
- Diagnosed with Glioblastoma (per EMR)
- Has not yet started radiation and concurrent temozolomide treatment (per EMR)
- Has a primary neuro-oncologist at MSK (per EMR)
- Will be undergoing radiation at MSK (per EMR)
- Treatment plan consists of a 6-week or 3-week (hypofractionated) course of radiation and chemotherapy (per EMR)
- Participant or caregiver is fluent in English or Spanish
- Planning on remaining in the tri-state area during the 6 weeks or 3 weeks of radiation and chemotherapy (per self-report)
- Screens positive on SDOH screening tool, referred by the clinical team through traditional screening tools for SDOH assistance (per EMR or self-report), demonstrates financial need per MSK guidelines (up to 500% of the federal poverty limit), and/or requests help with SDOH resources or navigation Participant
Exclusion criteria
- Patient is ineligible if he/she is:
- Diagnosed with Stage IV disease
- Presence of untreated psychiatric disturbance (i.e. acute psychiatric symptoms which require individual treatment) and/or cognitive impairment disorder (e.g., delirium or dementia) verified by medical record sufficient to preclude completion of the assessment measures, interview or informed consent
- Has another family member already enrolled in ICCAN (as determined by patient report) ICCAN-IO Phase 1: Refinement, participant is ineligible if he/she per EMR or self-report:
- Presence of untreated psychiatric disturbance (e.g., acute psychiatric symptoms which require individual treatment) and/or cognitive impairment disorder (e.g., delirium or dementia) sufficient to preclude completion of the assessment measures, interview or informed consent
- Participants or family members who are participating in MSK IHCD studies related to social determinants of health ICCAN-IO Phase 2: Pilot RCT, participant is ineligible if he/she per EMR or self-report:
- Presence of untreated psychiatric disturbance (e.g, acute psychiatric symptoms which require individual treatment) and/or cognitive impairment disorder (e.g., delirium or dementia) sufficient to preclude completion of the assessment measures, interview or informed consent
- Participants or family members who are participating in MSK IHCD studies related to social determinants of health at the PI's discretion ICCAN-GBM
- No recurrences - must be newly diagnosed glioblastoma (per EMR)
- Patients undergoing different treatment regimens from the 15 fraction/3 week or 30 fraction/6 week course of radiation (i.e. patients undergoing 10 fractions of palliative radiation due to poor functional status) (per EMR)
- Presence of untreated psychiatric disturbance (i.e. acute psychiatric symptoms that require individual treatment) (per EMR or self-report)
- Severe cognitive impairment or fluent aphasia as not to understand the assessment measures, interview, or informed consent, without a health care proxy or caregiver that can assist as indicated by clinician or per judgement of study staff. Completion of assessments with the help of caregivers is acceptable. (per EMR or self-report)
- Has another family member or household member already enrolled in ICCAN (per self-report)
- Already participated in or already completed the ICCAN program (per self-report)
Where
- Basking Ridge, New Jersey
- Middletown, New Jersey
- Montvale, New Jersey
- Brooklyn, New York
- Commack, New York
- Harrison, New York
- New York, New York
- Rockville Centre, New York
- The Bronx, New York
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Jun 12, 2026 · Source of record for eligibility and locations