NCT06282510 · Mary K Hayden
Nasal Antisepsis for C. Auris Prevention
What this study is about
This is a randomly assigned, controlled, where both patients and doctors know the treatment given trial of effect of 10% povidone iodine intranasal antisepsis on the detection of Candida auris.
View original scientific description
This is a randomized, controlled, open-label trial of effect of 10% povidone iodine intranasal antisepsis on the detection of Candida auris.
Interventions
DRUG
Povidone Iodine Topical
Topical intranasal povidone iodine (10%) twice daily for 5 days
Primary outcome measures
Detection of C. auris from the anterior nares
Time frame: Through study completion and data analysis in three years (2028)
Culture detection of C. auris from anterior nares on intervention day 5.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- History of C. auris colonization or infection
- Patient in a participating facility
Exclusion criteria
- History of severe allergy to iodine-based products, defined as anaphylaxis or rash
- Currently breastfeeding or pregnant
- Non-English language speaking
Where
- Chicago, Illinois
- Hinsdale, Illinois
Collaborators
Rush University Medical Center, RML Specialty Hospital
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Oct 15, 2025 · Source of record for eligibility and locations