Durham, NCNCT06644742Now EnrollingIRB Ready

Cardiomyopathies Clinical Trial in Durham, NC

Access cutting-edge cardiomyopathies treatment through this clinical trial at a research site in Durham. Study-provided care at no cost to qualified participants.

Sponsored by Rocket Pharmaceuticals Inc.

Quick Self-Assessment

See if you qualify for this Durham location

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Expert Care in Durham

Access cardiomyopathies specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related cardiomyopathies treatment provided free

Apply for This Durham Location

Check if you qualify for this cardiomyopathies clinical trial in Durham, NC

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Durham

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Durham site if eligible
  4. 4Begin participation

About This Cardiomyopathies Study in Durham

The goal of this study is to describe the natural history and clinical events for patients who have Arrhythmogenic Cardiomyopathy with Pathogenic Plakophilin-2 Variants (PKP2-ACM) managed with standard of care.

Sponsor: Rocket Pharmaceuticals Inc.

Who Can Participate

Inclusion Criteria

Patients must meet all the following criteria (and none of the

Exclusion Criteria

) to be eligible for study participation:
Male or female age 12 years or older at the time of providing informed consent (i.e., ICF provision).
Capable and willing to provide signed informed consent and/or assent, which includes compliance with the requirements and restrictions listed in the ICF and protocol.
Clinical diagnosis of arrhythmogenic cardio myopathy (ACM)
Documentation of a pathogenic or likely pathogenic variant in PKP2 by a CLIA-certified genetic testing laboratory
History of ICD implantation ≥6 months prior to ICF provision
Left ventricular ejection fraction by echocardiogram or cardiac magnetic resonance (CMR) ≥50% at ≤12 months prior to ICF provision Exclusion Criteria Patients meeting any of the following criteria are excluded from study participation:
Gene testing indicates that the subject's arrhythmia or cardiomyopathy may be related to a genetic etiology other than PKP2 truncating variant.
Concurrent participation in any other clinical investigation involving use of an investigational agent that could confound results of this study.
Previous participation in a study of gene transfer or gene editing.
NYHA Class IV heart failure.
Presence or requirement for mechanical circulatory support (MCS) or predicted need for MCS or heart transplantation within 6 months of enrollment.
Prior cardiac or other organ (lung, liver, other) transplantation.
Pacemaker dependent rhythm documented, as assessed by the principal investigator ≤12 months prior to enrollment.
Positive human immunodeficiency virus (HIV) antibody test.
Unwillingness to comply with study procedures, including follow-up as specified by this protocol, or unwillingness to fully cooperate with the investigator.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Durham?

Yes, this clinical trial (NCT06644742) has an active research site in Durham, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Cardiomyopathies Treatment Options in Durham, NC

If you're searching for cardiomyopathies treatment options in Durham, NC, this clinical trial (NCT06644742) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Durham research site is actively enrolling participants for this clinical trial. You'll receive care from experienced cardiomyopathies specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Ready to Join in Durham?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Durham, NC