Providence, RINCT05990881Now EnrollingIRB Ready

Carpometacarpal Sprain Clinical Trial in Providence, RI

Access cutting-edge carpometacarpal sprain treatment through this clinical trial at a research site in Providence. Study-provided care at no cost to qualified participants.

Sponsored by Rhode Island Hospital

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Expert Care in Providence

Access carpometacarpal sprain specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related carpometacarpal sprain treatment provided free

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Check if you qualify for this carpometacarpal sprain clinical trial in Providence, RI

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Why Participate?

  • No-Cost Study Care

  • Local to Providence

    Convenient for RI residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Providence site if eligible
  4. 4Begin participation

About This Carpometacarpal Sprain Study in Providence

The purpose of this clinical trial is to gather information on the safety and effectiveness of botulinum toxin injection (or Botox) in the treatment of thumb joint pain/arthritis. People with thumb joint pain or arthritis usually receive steroid injections to help with the pain. However, this medicine does not always work well and also carries known important side effects. There is currently no alternative to this injection medicine. This clinical trial seeks to investigate botulinum toxin as a possible alternative to steroid injection. The difference between Botox and steroid injections is that they are different medicines and work in different ways. Botox, as it is being used in this study, is not FDA-approved. It is therefore considered an investigational medicine.

Sponsor: Rhode Island Hospital

Who Can Participate

Inclusion Criteria

Adult patients (\> 18 years old) with a diagnosis of thumb CMC OA
Diagnosis of thumb CMC OA
History, clinical exam, and radiographic findings, as done in prior studies on this topic.
Subjective: thumb or wrist pain at rest or with activity, joint stiffness
Exam: basal joint tenderness, decreased mobility, deformity, instability
Radiograph: joint space narrowing, subchondral sclerosis, osteophytes, subchondral cysts, Eaton-Littler stage.
Failed conservative management with oral pain medication and splinting for at least 3 months.

Exclusion Criteria

Severe osteoarthritis (Eaton-Littler stage 4) or too large osteophytes to allow for injection into the joint space Inflammatory arthritis
Any concomitant hand conditions (i.e. carpal tunnel, trigger finger, etc)
Prior significant hand trauma related to the thumb or first CMC joint
Prior intervention or hand surgery
Patients with fibromyalgia or complex regional pain syndrome (CRPS)
Pregnant and breastfeeding patients will also be excluded. We also will exclude individuals attempting to conceive or who could become pregnant within 6-months of treatment.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Providence?

Yes, this clinical trial (NCT05990881) has an active research site in Providence, RI that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Carpometacarpal Sprain Treatment Options in Providence, RI

If you're searching for carpometacarpal sprain treatment options in Providence, RI, this clinical trial (NCT05990881) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Providence research site is actively enrolling participants for this clinical trial. You'll receive care from experienced carpometacarpal sprain specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all carpometacarpal sprain clinical trials near you to find additional studies recruiting in your area.

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