Colorado Springs, CONCT07745361Now EnrollingIRB Ready

Castration-Resistant Prostate Cancer (CRPC) Clinical Trial in Colorado Springs, CO

Access cutting-edge castration-resistant prostate cancer (crpc) treatment through this phase 2 clinical trial at a research site in Colorado Springs. Study-provided care at no cost to qualified participants.

Sponsored by Monte Rosa Therapeutics, Inc

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Expert Care in Colorado Springs

Access castration-resistant prostate cancer (crpc) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related castration-resistant prostate cancer (crpc) treatment provided free

Apply for This Colorado Springs Location

Check if you qualify for this castration-resistant prostate cancer (crpc) clinical trial in Colorado Springs, CO

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Colorado Springs

    Convenient for CO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Colorado Springs site if eligible
  4. 4Begin participation

About This Castration-Resistant Prostate Cancer (CRPC) Study in Colorado Springs

This Phase 2, open-label, multicenter study is conducted in patients with castration-resistant prostate cancer. Patients in this study receive MRT-2359, an investigational oral medicine, in combination with apalutamide, an oral medicine used to treat prostate cancer. The main purpose of the study is to assess whether this treatment combination can lower prostate-specific antigen (PSA) The study will also evaluate the safety and tolerability of the treatment combination and assess additional measures of anti-tumor activity.

Sponsor: Monte Rosa Therapeutics, Inc

Who Can Participate

Inclusion Criteria

Age \> 18 years
A predicted life expectancy of ≥ 3 months and an ECOG performance status ≤ 1
Have histologically or cytologically confirmed castration-resistant adenocarcinoma of the prostate without small cell histology and with androgen receptor (AR) mutations
Have not had prior treatment with more than 1 prior taxane-based chemotherapy regimen for castration-resistant prostate cancer
Have no prior treatment with an AR degrader, opevesostat, or similar therapy
Has ongoing (chemical or surgical) androgen deprivation with serum testosterone \< 50 ng/dL (\< 1.7 nM)
Has received prior treatment with poly(ADP-ribose) polymerase (PARP) inhibitor, if appropriate, or deemed ineligible to receive treatment by the Investigator, or has refused PARP inhibitor treatment
Has received prior treatment with at least 1 line of ARPi
Have disease measurable per Prostate Cancer Working Group 4 (PCWG4) criteria, with or without measurable disease by RECIST 1.1
Be able to provide a tumor biopsy for biomarker analysis during the Screening period
Have adequate organ function

Exclusion Criteria

• Have received prior chemotherapy, definitive radiation, or biological cancer therapy within 21 days before the first dose of study treatment or have any AEs that have failed to recover to baseline
Have received prior therapy with a GSPT1 degrader that was discontinued due to an AE
Have received prior auto-HCT and have not fully recovered from effects of the last transplant
Have received allogeneic hematopoietic stem cell transplantation within past 6 months and/or have symptoms of graft-versus-host disease
Current use of chronic systemic steroid therapy in excess of replacement doses
Have clinically active central nervous system involvement and/or carcinomatous meningitis
Have a confirmed history of (noninfectious) pneumonitis that required steroids
Clinically significant cardiac disease

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Colorado Springs?

Yes, this clinical trial (NCT07745361) has an active research site in Colorado Springs, CO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Castration-Resistant Prostate Cancer (CRPC) Treatment Options in Colorado Springs, CO

If you're searching for castration-resistant prostate cancer (crpc) treatment options in Colorado Springs, CO, this clinical trial (NCT07745361) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Colorado Springs research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced castration-resistant prostate cancer (crpc) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all castration-resistant prostate cancer (crpc) clinical trials near you to find additional studies recruiting in your area.

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