NCT06215105 · Microvention-Terumo, Inc.
Complex Aneurysm Registry - Real-World Evidence Data Collection for Intracranial Aneurysm Treatment Devices
(CAR)
What this study is about
To collect real-world evidence allowing assessment of functional, imaging, and safety outcomes of commercially available MicroVention devices used for the endovascular treatment of intracranial aneurysms (IA) at the direction of the treating physician.
View original scientific description
To collect real-world evidence allowing assessment of functional, imaging, and safety outcomes of commercially available MicroVention devices used for the endovascular treatment of intracranial aneurysms (IA) at the direction of the treating physician.
Interventions
DEVICE
Commercially available MicroVention Intracranial Aneurysm Treatment Devices
Commercially available MicroVention intracranial aneurysm treatment devices used in routine clinical practice for the endovascular treatment of intracranial aneurysms. Device selection and treatment decisions are made by the treating physician according to standard clinical practice and are not assigned by the registry.
Primary outcome measures
RROC
Time frame: 1 year
Angiographic aneurysm occlusion (RROC) at 1 year
RROC
Time frame: 1 year
Angiographic aneurysm occlusion (RROC) at 1 year without rebleed (ruptured aneurysms only)
RROC
Time frame: 1 year
Angiographic aneurysm occlusion (RROC) at 1 year without rebleed (ruptured aneurysms only) or retreatment for residual aneurysm
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Patient must have a single ruptured or unruptured IA for which endovascular treatment has been determined appropriate.
- Patient will be treated using a commercially available MicroVention implant device as the primary treatment device and the decision to use this device has been made by the treating physician outside the context of the CAR study and prior to enrollment. Note: For the purposes of this protocol, ancillary/accessory devices such as balloon catheters and other access devices are not considered primary treatment devices.
- Patient or patient 's legally authorized representative (LAR) has provided written informed consent prior to treatment and no later than 48 hours post procedure for emergent treatment of ruptured aneurysms.
- Patient must be considered by the treating physician to be available for and able to complete study follow-up visits.
Exclusion criteria
- Target aneurysm has been previously treated via surgical or endovascular means.
- Patient is enrolled in another device or drug study in which participation could confound study results.
- Patient has a life expectancy of less than 1 year due to other illness or condition (in addition to an intracranial aneurysm).
- Patient has been previously enrolled into this study.
Where
- Walnut Creek, California
- Englewood, Colorado
- Hartford, Connecticut
- Fort Lauderdale, Florida
- Hollywood, Florida
- Jacksonville, Florida
- Miami Beach, Florida
- Orlando, Florida
- Tampa, Florida
- Honolulu, Hawaii
- Iowa City, Iowa
- Louisville, Kentucky
And 15 more locations — see the full list below.
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Nov 10, 2026 · Source of record for eligibility and locations