NCT00900575 · Duke University
Cervical Cancer Detection Using Optical Spectroscopy
What this study is about
The objective of the work described in this protocol is to determine the optical signatures of cervical dysplasia using optical technologies.
View original scientific description
The objective of the work described in this protocol is to determine the optical signatures of cervical dysplasia using optical technologies.
Interventions
DEVICE
Optical Spectroscopy Bench-Top System
This device is a bench-top optical spectrometer
DEVICE
Portable Optical Spectrometer
This device is a portable optical spectrometer
DEVICE
Transvaginal colposcope
Primary outcome measures
Identification of optical signatures of cervical tissue
Time frame: Day of procedure (less than 10 minutes)
The primary outcome of this study is the identification of the optical signatures of cervical tissue.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- undergoing colposcopy for the diagnosis of cervical cancer
- LEEP for the treatment of cervical cancer in early stages.
- Follow-up Pap smear in surveillance
Exclusion criteria
- Women under the age of 18 (minors) will be excluded from this study.
- patients will be excluded if she has had a recent episode of bleeding or preterm labor.
- Subjects who are not competent to give consent will excluded
Where
- Durham, North Carolina
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Mar 6, 2026 · Source of record for eligibility and locations