Irvine, CANCT04831580Now EnrollingIRB Ready

Cervical Cancer Clinical Trial in Irvine, CA

Access cutting-edge cervical cancer treatment through this clinical trial at a research site in Irvine. Study-provided care at no cost to qualified participants.

Sponsored by GOG Foundation

Quick Self-Assessment

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Expert Care in Irvine

Access cervical cancer specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related cervical cancer treatment provided free

Apply for This Irvine Location

Check if you qualify for this cervical cancer clinical trial in Irvine, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Irvine

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Irvine site if eligible
  4. 4Begin participation

About This Cervical Cancer Study in Irvine

This is a randomized controlled trial to compare survival for patients who undergoe robotic assisted laparoscopy versus open hysterectomy and lymph node assessment for the treatment of early stage cervical cancer.

Sponsor: GOG Foundation

Who Can Participate

Inclusion Criteria

Patient must have histologically confirmed adenocarcinoma (usual/classic/NOS), squamous cell carcinoma, adenosquamous carcinoma (Including glassy cell)
Patient must be FIGO Stage IA2, IBI, IB2 (2018 staging) without evidence of definitive parametrial, vaginal, nodal or distant metastases on exam or imaging. Patients with tumor size less than or equal to 4 cm confirmed on MRI prior to randomization are eligible.
Patient must have uterine size \<12 cm AND felt to be appropriate for vaginal delivery of the specimen per investigator.
Patient must be suitable surgical candidate with preoperative assessments such as labs and EKG performed per institutional standard and agree to be randomized to undergo open or robotic radical (or simple) hysterectomy. NOTE: Simple hysterectomy will be allowed in patients who meet the following criteria:
pelvic MRI must demonstrate a maximal tumor size of 2 cm or less AND
less than 50% stromal invasion on MRI if tumor present or less than 10 mm of stromal invasion if an excisional (cold knife or LEEP) has been performed. Submission of source documents in the GOG Partners Source Document Portal will be required prior to randomization for review and confirmation of simple hysterectomy being met (see Section 6.0 for instructions).
Patient must be age 18 years or older.
Patient must have ECOG performance status 0-1.
Patient must have a negative urine pregnancy test within 30 days of surgery in pre-menopausal women.
Patient must have signed an approved informed consent and authorization permitting the release of personal health information.

Exclusion Criteria

Patients with any tumor histology other than those listed above, specifically excluding the following histologies: neuroendocrine, other adenocarcinoma (gastric type, endometrioid, clear cell, serous, signet ring, minimal deviation)
Patients with FIGO stage 1A1, IB3, II-IV (2018 staging).
Patient with inability to receive an MRI.
Patients with a tumor size greater than 4cm or on MRI confirmed prior to randomization are excluded. Patients with definite evidence of vaginal/parametrial involvement on MRI are excluded; if MRI findings are not definitive, then clinical examination must also not reveal parametrial or vaginal extension).
Patients with evidence of metastatic disease (imaging or histologically positive lymph nodes).
Patients with a history of prior pelvic or abdominal radiotherapy.
Patients with a prior malignancy \< 5 years from enrollment with the exception of non-melanoma skin cancer.
Patients who are unable to withstand prolonged lithotomy or steep trendelenberg.
Patient compliance and geographic proximity that do not allow adequate follow-up.
Patients with poorly controlled HIV with CD4 counts \<500.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Irvine?

Yes, this clinical trial (NCT04831580) has an active research site in Irvine, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Cervical Cancer Treatment Options in Irvine, CA

If you're searching for cervical cancer treatment options in Irvine, CA, this clinical trial (NCT04831580) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Irvine research site is actively enrolling participants for this clinical trial. You'll receive care from experienced cervical cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all cervical cancer clinical trials near you to find additional studies recruiting in your area.

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