NCT05805410 · Shirley Ryan AbilityLab
Neuromuscular Mechanisms of Specific Trunk Interventions in Children With CP
What this study is about
Determine the effect of repeated pelvis perturbation training on trunk posture and locomotor function in children with CP.
View original scientific description
Determine the effect of repeated pelvis perturbation training on trunk posture and locomotor function in children with CP.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Children with a diagnosis of bilateral spastic CP attributed to complications of prematurity, intracranial hemorrhage and periventricular leukmalacia according to the definition of Bax.
- Children aged 4 to 12 years old without Botulinum toxin treatment within 6 months, and without surgeries (such as selective dorsal rhizotomy) within 12 months before the onset of the training.
- Subjects will be able to remain seated without help for ≥10s.
- GMFCS levels will be I to IV.
- Children must be able to signal pain, fear or discomfort reliably.
- Children with mild scoliosis (Cobb angle \< 20 °).
- Children with CP who have no prior hippotherapy experiences within 6 months.
Exclusion criteria
- severe lower extremity contractures, fractures, osseous instabilities, osteoporosis.
- severe disproportional bone growth.
- unhealed skin lesions in the lower extremities.
- thromboembolic diseases, cardiovascular instability.
- aggressive or self-harming behaviors.
Where
- Chicago, Illinois
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Jun 3, 2025 · Source of record for eligibility and locations