Jacksonville, FLNCT06077747Now EnrollingIRB Ready

Chronic Headache Clinical Trial in Jacksonville, FL

Access cutting-edge chronic headache treatment through this clinical trial at a research site in Jacksonville. Study-provided care at no cost to qualified participants.

Sponsored by Mayo Clinic

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Expert Care in Jacksonville

Access chronic headache specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related chronic headache treatment provided free

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Check if you qualify for this chronic headache clinical trial in Jacksonville, FL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Jacksonville

    Convenient for FL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Jacksonville site if eligible
  4. 4Begin participation

About This Chronic Headache Study in Jacksonville

The purpose of this research is to gather information on the safety and feasibility of coiling the lumbar vein for the treatment of chronic headaches in patients with Nutcracker physiology and retrograde lumbar vein flow with epidural venous plexus congestion. All patients are extensively evaluated by a headache trained Neurologist confirming high pressure headache refractory to other treatments.

Sponsor: Mayo Clinic

Who Can Participate

Inclusion Criteria

Daily headache from onset lasting \> 3 months.
Headache described as pressure sensation.
Headache worsened in the Trendelenburg position.
Exposed to CSF pressure/volume lowering medications.
Tried 2 of 4 unless contraindications: acetazolamide, methazolamide, indomethacin SR or spironolactone) or CSF volume removal via LP with positive or neutral response.
Failed at least 3 typical headache preventative medications from different classes-antidepressants, antiepileptic, blood pressure medications.
MRI demonstrates that Nutcracker physiology is present.
Decreased SMA angle, renal vein narrowing, decreased AMD.
Retrograde lumbar vein flow and early EVP enhancement.
Ability to understand study procedures and to comply with them for the entire length of the study.
Negative pregnancy test.

Exclusion Criteria

Evidence of disc edema.
Positive urinalysis for hematuria or proteinuria.
Abnormal CBC or CMP.
MRI, MRA head and neck and MR venogram with a possible secondary causes of headache including space occupying lesions, Chiari malformation, cerebral vein thrombosis, hydrocephalus, dissection, aneurysm etc.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Jacksonville?

Yes, this clinical trial (NCT06077747) has an active research site in Jacksonville, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Chronic Headache Treatment Options in Jacksonville, FL

If you're searching for chronic headache treatment options in Jacksonville, FL, this clinical trial (NCT06077747) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Jacksonville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced chronic headache specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all chronic headache clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Jacksonville, FL