Aurora, CONCT07194590Now EnrollingIRB Ready

Chronic Kidney Disease (Stage 3-4) Clinical Trial in Aurora, CO

Access cutting-edge chronic kidney disease (stage 3-4) treatment through this clinical trial at a research site in Aurora. Study-provided care at no cost to qualified participants.

Sponsored by University of Colorado, Denver

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Expert Care in Aurora

Access chronic kidney disease (stage 3-4) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related chronic kidney disease (stage 3-4) treatment provided free

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Check if you qualify for this chronic kidney disease (stage 3-4) clinical trial in Aurora, CO

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Why Participate?

  • No-Cost Study Care

  • Local to Aurora

    Convenient for CO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Aurora site if eligible
  4. 4Begin participation

About This Chronic Kidney Disease (Stage 3-4) Study in Aurora

The risk of cardiovascular disease (CVD) is significantly elevated in patients with chronic kidney disease (CKD). Notably, women with CKD commonly experience menstrual disturbances induced by CKD, which may contribute to impaired vascular function and elevated CVD risk. However, most of the literature in nephrology focuses on male patients, and studies on women's vascular health are limited. Establishing effective therapies for improving vascular function and reducing CVD risk in women with CKD is a high research priority of the NIH. Equol contributes to improvement in vascular function, mediated in part by its anti-oxidative and anti-inflammatory properties. However, there is no information on the effect of equol on vascular function in women with CKD. The proposed project aims to determine the effect of 12 weeks of oral equol supplementation on vascular function in postmenopausal women with CKD.

Sponsor: University of Colorado, Denver

Who Can Participate

Inclusion Criteria

Postmenopausal women
Aged ≥50 years
CKD stage 3 or 4 (eGFR with the CKD-EPI 2021 race-free equation: 15-59 mL/min/1.73m2; stable renal function in the past 3 months)
Low habitual intake of soy (soy-related food intake \< 2 times per week assessed by Soy-Specific Food Frequency Questionnaire)
Weight stable in the prior 3 months (\<2 kg weight change) and willing to remain weight stable throughout the study
Ability to provide informed consent.

Exclusion Criteria

Patients with advanced CKD requiring chronic dialysis
Uncontrolled hypertension in CKD group (BP \>140/90 mmHg)
Use of any hormone replacement therapy
Allergy and/or intolerance to soy or soy-based products
Aspartate aminotransferase (AST), alanine aminotransferase (ALT), or total bilirubin values 2X upper limit of normal range (upper limit of normal range AST: 117 U/L; ALT: 52 U/L; total bilirubin: 1.3 mg/dL)
History of breast cancer
Significant co-morbid conditions with a life expectancy of \< 1 year
Current tobacco or nicotine use or history of use in the last 12 months
History of kidney transplant
History of severe congestive heart failure (i.e., ejection fraction \<35%)
History of hospitalization within the last month
Immunosuppressant agents taken in the past 12 months
Known malignancy

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Aurora?

Yes, this clinical trial (NCT07194590) has an active research site in Aurora, CO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Chronic Kidney Disease (Stage 3-4) Treatment Options in Aurora, CO

If you're searching for chronic kidney disease (stage 3-4) treatment options in Aurora, CO, this clinical trial (NCT07194590) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Aurora research site is actively enrolling participants for this clinical trial. You'll receive care from experienced chronic kidney disease (stage 3-4) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all chronic kidney disease (stage 3-4) clinical trials near you to find additional studies recruiting in your area.

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