Washington Dc, DCNCT06110130Now EnrollingIRB Ready

Chronic Kidney Diseases Clinical Trial in Washington Dc, DC

Access cutting-edge chronic kidney diseases treatment through this phase 4 clinical trial at a research site in Washington Dc. Study-provided care at no cost to qualified participants.

Sponsored by Washington D.C. Veterans Affairs Medical Center

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Expert Care in Washington Dc

Access chronic kidney diseases specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related chronic kidney diseases treatment provided free

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Check if you qualify for this chronic kidney diseases clinical trial in Washington Dc, DC

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Washington Dc

    Convenient for DC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Washington Dc site if eligible
  4. 4Begin participation

About This Chronic Kidney Diseases Study in Washington Dc

Primary Objective:To study podocyte specific injury markers in African American Veterans with non-diabetic kidney disease(NDKD), on empagliflozin therapy. Primary Endpoint: Assess the effect of Empagliflozin on podocyte-specific proteins in exosomes isolated from subjects' urine, such as nephrin, podocalyxin and Wilms'Tumor (WT-1) protein. Secondary Objective: 1. Correlate changes in exosome-based podocyte specific proteins with standardized biomarkers of kidney injury including urine albumin/creatinine ratio (ACR) and estimated GFR. 2. Correlate systemic inflammatory markers (focusing on vascular and endothelial function) that are already established such as interleukins (IL1, IL6, IL-12) , hs-CRP and arterial stiffness measures with urine exosome-based podocyte protein estimation. 3. Correlate urine podocyte-specific protein markers with APOL1 mRNA expression levels in blood mononuclear cells (MNC)

Sponsor: Washington D.C. Veterans Affairs Medical Center

Who Can Participate

Inclusion Criteria

African American veterans
Age \> 18 years
eGFR ≥20-59 mL/min/1.73 m2 by the CKD-EPI equation, with or without any degree of albuminuria OR
eGFR 60-89, with UACR of ≥30mg/g
BMI = 18-39.9
Blood pressure controlled to ≤140/90
Subjects without diabetes: will be screened using routine glucose level test: of less than 126 fasting glucose or less than 200mg/dl of random or post glucose blood glucose level in standard of care laboratory workup.
Ability to provide informed consent before any trial related activities are conducted.

Exclusion Criteria

Diagnosed with Type 1 or Type 2 Diabetes Mellitus
Any prescribed diabetes medication for patients, such as GLP1RA, SGLT2is, and sulphonylureas
If a patient is on statin, need to be on a stable dose for a month.
Biopsy proven diagnosis of glomerular disease/glomerulonephritis
Active smokers,
Active skin wounds undergoing treatment or recent surgery within 1 month (due to possible aberrations in glycemic control)
Women who are pregnant, planning to become pregnant, nursing mothers, women of childbearing potential not using birth control measure
Hypersensitivity to empagliflozin or any of the excipients in Jardiance, reactions such as angioedema
Patients on dialysis
eGFR less than 20 mL/min/1.73 m2 by the CKD-EPI equation
Planned surgery or planned hospital admission within 5 months of participation in the study
At the discretion of PI to ensure health, safety, and well-being of the veteran, participation in this study may be stopped (please see withdrawal criteria)
Patients with prior history of diagnosis of heart failure with documented EF of less than 50.
Proven diagnosis of Polycystic Kidney Disease.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Washington Dc?

Yes, this clinical trial (NCT06110130) has an active research site in Washington Dc, DC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Chronic Kidney Diseases Treatment Options in Washington Dc, DC

If you're searching for chronic kidney diseases treatment options in Washington Dc, DC, this clinical trial (NCT06110130) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Washington Dc research site is actively enrolling participants for this phase 4 clinical trial. You'll receive care from experienced chronic kidney diseases specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all chronic kidney diseases clinical trials near you to find additional studies recruiting in your area.

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