NCT06624358 · Children's Hospital of Philadelphia
Physical Activity in CKD
(PACKD)
What this study is about
The goal of this is to test the effectiveness of a 12-week physical activity intervention in 64 adolescents with CKD.
View original scientific description
The goal of this is to test the efficacy of a 12-week physical activity intervention in 64 adolescents with CKD.
Interventions
BEHAVIORAL
Increase Physical Activity
Behavioral interventions to improve physical activity
Primary outcome measures
Change in time spent in moderate to vigorous physical activity (minutes/day)
Time frame: pre 12 week intervention and post 12 week intervention
Change in time spent in moderate to vigorous physical activity measured by Fitbit over the course of 12 weeks
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- For adolescent participants:
- Males or females age 13 - 18 years
- Diagnosis of CKD stage II - V not yet on dialysis or with a transplant
- English proficiency
- Parental/guardian permission (informed consent), and if applicable, child assent For caregiver participants:
- Parent/legal guardian of an enrolled adolescent participant
- English proficiency
Exclusion criteria
- For adolescent participants:
- Pregnant or lactating
- Non-ambulatory
- Have high physical activity at baseline (\>45 min/day of MVPA)
- Provide \<2 days of physical activity data during the run-in period
- Have a condition, such as heart or lung disease, that preclude safely engaging in physical activity
- Have received a solid organ transplant
- Have limited English proficiency
- Are on dialysis
- In the opinion of the investigator, are unable to comply with the requirements of the study protocol or are unsuitable for the study for any reason For caregivers participants: 1\. Limited English proficiency
Where
- Philadelphia, Pennsylvania
Collaborators
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Oct 2, 2025 · Source of record for eligibility and locations