Cleveland, OHNCT05296408Now EnrollingIRB Ready

Chronic Stroke Clinical Trial in Cleveland, OH

Access cutting-edge chronic stroke treatment through this clinical trial at a research site in Cleveland. Study-provided care at no cost to qualified participants.

Sponsored by VA Office of Research and Development

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Expert Care in Cleveland

Access chronic stroke specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related chronic stroke treatment provided free

Apply for This Cleveland Location

Check if you qualify for this chronic stroke clinical trial in Cleveland, OH

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Cleveland

    Convenient for OH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Cleveland site if eligible
  4. 4Begin participation

About This Chronic Stroke Study in Cleveland

This study will evaluate the effects of combining motor learning-based therapy with use of the MyoPro , a wearable exoskeletal myoelectrically controlled orthotic device. MyoPro uses electromyographic (EMG) signals from the weak muscles to assist movement of the user's affected arm. The primary objective of this randomized controlled trial is to study the efficacy of using MyoPro in motor learning-based therapy for individuals with chronic stroke (\>6 months post) with severe upper limb motor deficits (Fugl-Meyer for Upper Limb score less than 30) compared with a similar dose of motor learning-based therapy alone. The secondary objectives are to evaluate neuroplasticity mechanisms, identify biomarkers of greater response to the intervention, and explore cost-effectiveness.

Sponsor: VA Office of Research and Development

Who Can Participate

Inclusion Criteria

18-89 years of age
Unilateral arm weakness due to stroke (6 months or more since onset)
Adequate range of motion at the elbow, forearm, wrist, and hand to don the device
Active shoulder flexion of at least 30 degrees and active shoulder abduction of at least 20 degrees
Ability to generate volitional, consistent, and detectable EMG signals from the upper arm and forearm sensor sites with wrist in neutral or flexed positions as detected by the MyoPro software
MAS score less or equal to 3 for the biceps, triceps, supinators and pronators of the impaired arm
Able to read and comprehend the English language
Able to follow directions
Able to provide informed consent
Medically and psychologically stable.
Ability to don/doff MyoPro independently or have support as needed.
Ability to undergo MRI
Ability to undergo TMS procedures

Exclusion Criteria

Previous stroke(s) affecting motor function on the opposite side.
Persistent and severe shoulder subluxation, pain or dislocation
Shoulder passive range of motion \< 45 degrees in flexion and abduction
Fixed upper limb contractures on the impaired arm and hand
Unable to safely support the weight of their arm plus 4 lbs (1.82 kg; the weight of the device) without pain even with arm supported.
Skin rash or open non-healing wound on impaired arm
Involuntary movements of the impaired arm
Pacemaker or other implanted devices that are not compatible with testing procedures or would interfere with donning/doffing and functioning of device.
Metal in the skull or deformity of the skull
Claustrophobia, or inability to operate the MRI patient call button
Contraindications for MRI (standardized screening form for MRI).
Past history of seizures
Family history of medication refractory epilepsy
Pregnancy or pregnancy planning during the study period
Currently taking medications or substances that lower the threshold for onset of seizure.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Cleveland?

Yes, this clinical trial (NCT05296408) has an active research site in Cleveland, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Chronic Stroke Treatment Options in Cleveland, OH

If you're searching for chronic stroke treatment options in Cleveland, OH, this clinical trial (NCT05296408) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Cleveland research site is actively enrolling participants for this clinical trial. You'll receive care from experienced chronic stroke specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all chronic stroke clinical trials near you to find additional studies recruiting in your area.

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