Bethesda, MDNCT05804669Now EnrollingIRB Ready

Cushing Syndrome Clinical Trial in Bethesda, MD

Access cutting-edge cushing syndrome treatment through this clinical trial at a research site in Bethesda. Study-provided care at no cost to qualified participants.

Sponsored by Crinetics Pharmaceuticals Inc.

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Expert Care in Bethesda

Access cushing syndrome specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related cushing syndrome treatment provided free

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Check if you qualify for this cushing syndrome clinical trial in Bethesda, MD

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Bethesda

    Convenient for MD residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Bethesda site if eligible
  4. 4Begin participation

About This Cushing Syndrome Study in Bethesda

A Phase 1b/2a, first-in-disease, open-label, multiple-ascending dose exploratory study to evaluate safety, tolerability, pharmacokinetics (PK), and pharmacodynamic biomarker responses associated with CRN04894 (an adrenocorticotropic hormone \[ACTH\] receptor antagonist) in participants with ACTH-dependent Cushing's syndrome (Cushing's disease or Ectopic ACTH Syndrome \[EAS\])

Sponsor: Crinetics Pharmaceuticals Inc.

Who Can Participate

Inclusion Criteria

Adult male or female, aged 18 years or more
Evidence of chronic 'active' ACTH-dependent Cushing's syndrome
Evidence of acutely 'active' ACTH-dependent Cushing's syndrome within 10 days of Day 1
Participants with documented ACTH-dependent Cushing's syndrome taking short-acting steroidogenesis inhibitors (ketoconazole, levoketoconazole, osilodrostat, or metyrapone) may participate after a washout period of at least 5 days, if they meet other study inclusion criteria, relative to Investigator's judgment. Participants with documented ACTH-dependent Cushing's syndrome taking cabergoline may participate after a washout period of at least 14 days, if they meet other study inclusion criteria

Exclusion Criteria

Women who are pregnant or lactating
History of bilateral adrenalectomy
Previous pituitary MRI findings of a putative ACTH-secreting lesion within 3 mm of the optic chiasm
Presence of any known malignancy
Use of mitotane
Previous unsuccessful surgery for Cushing's syndrome within 6 weeks

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Bethesda?

Yes, this clinical trial (NCT05804669) has an active research site in Bethesda, MD that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Cushing Syndrome Treatment Options in Bethesda, MD

If you're searching for cushing syndrome treatment options in Bethesda, MD, this clinical trial (NCT05804669) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Bethesda research site is actively enrolling participants for this clinical trial. You'll receive care from experienced cushing syndrome specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all cushing syndrome clinical trials near you to find additional studies recruiting in your area.

More Cushings Syndrome Trials in Bethesda, MD

See all cushings syndrome clinical trials recruiting in Bethesda — not just this study.

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