Charleston, WVNCT06764966Now EnrollingIRB Ready

Decompensated Liver Cirrhosis Clinical Trial in Charleston, WV

Access cutting-edge decompensated liver cirrhosis treatment through this clinical trial at a research site in Charleston. Study-provided care at no cost to qualified participants.

Sponsored by CAMC Health System

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Expert Care in Charleston

Access decompensated liver cirrhosis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related decompensated liver cirrhosis treatment provided free

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Check if you qualify for this decompensated liver cirrhosis clinical trial in Charleston, WV

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Charleston

    Convenient for WV residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Charleston site if eligible
  4. 4Begin participation

About This Decompensated Liver Cirrhosis Study in Charleston

Decompensated cirrhosis (liver disease) occurs when liver function decreases to the extent that serious complications develop and can include internal bleeding, fluid buildup in the abdomen, or mental confusion. This reduced decreased liver function subsequently decreases life expectancy. There is a critical need for strategies to delay progression to decompensation and reduce the occurrence of serious complications. Currently, limited therapeutic options are available for managing decompensated liver disease, with beta-blockers (BB) being the only proven medication with significant benefits in preventing disease progression. Statins have been historically under- prescribed in cirrhosis due to concerns of liver damage. However, there is emerging evidence that statin use may be beneficial and able to lessen liver disease worsening, with studies demonstrating its safety. Thus, we aim to conduct a pilot randomized controlled trial (RCT) study of 50 subjects comparing the outcomes of decompensated cirrhotic patients receiving the statin, atorvastatin, and a non-selective beta-blocker (NSBB) versus those receiving NSBB plus placebo. Both groups will be followed for 12 months to investigate the feasibility, safety, and efficacy of combination therapy.

Sponsor: CAMC Health System

Who Can Participate

Inclusion Criteria

Patients age of 18 years or older diagnosed with any form of decompensated liver disease defined as ascites, hepatic encephalopathy, or variceal bleed presenting at Charleston Area Medical Center (CAMC) Memorial Hospital or CAMC-Gastroenterology Liver Clinic
Currently on an non-selective beta-blockers agreeing to have their liver disease managed by CAMC-Gastroenterology Liver Clinic as an outpatient for the 12-month follow-up period.

Exclusion Criteria

Any patient \<18 years of age
Patients with hepatocellular carcinoma
Patients with ongoing alcohol use (self-reported consumption of more than one alcoholic drink per week)
Patients exhibiting high-risk behaviors that could put them at risk for complications including IV substance use and history of medication non-adherence
Patients currently on statin therapy
Patients with a history of statin intolerance
Patients on the waitlist for liver transplantation
Patients taking medications with known drug interactions with statins
Patients not able to give informed consent or patients belonging to vulnerable categories as the Federal Regulations or Common Rule

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Charleston?

Yes, this clinical trial (NCT06764966) has an active research site in Charleston, WV that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Decompensated Liver Cirrhosis Treatment Options in Charleston, WV

If you're searching for decompensated liver cirrhosis treatment options in Charleston, WV, this clinical trial (NCT06764966) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Charleston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced decompensated liver cirrhosis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all decompensated liver cirrhosis clinical trials near you to find additional studies recruiting in your area.

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