Minneapolis, MNNCT06325202Now EnrollingIRB Ready

Diabetes Mellitus, Type 1 Clinical Trial in Minneapolis, MN

Access cutting-edge diabetes mellitus, type 1 treatment through this clinical trial at a research site in Minneapolis. Study-provided care at no cost to qualified participants.

Sponsored by Milton S. Hershey Medical Center

Quick Self-Assessment

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Expert Care in Minneapolis

Access diabetes mellitus, type 1 specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related diabetes mellitus, type 1 treatment provided free

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Check if you qualify for this diabetes mellitus, type 1 clinical trial in Minneapolis, MN

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Minneapolis

    Convenient for MN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Minneapolis site if eligible
  4. 4Begin participation

About This Diabetes Mellitus, Type 1 Study in Minneapolis

The purpose of the CLEAR study is to determine the effect on counterregulatory responses (CRR) of intervening (by attempting to strictly avoid hypoglycemia) to improve awareness of hypoglycemic symptoms among adults with type 1 diabetes (T1D) who have impaired awareness of hypoglycemia (IAH). IAH affects 20-25% of adults with T1D, and rises with increasing duration of T1D.

Sponsor: Milton S. Hershey Medical Center

Who Can Participate

Inclusion Criteria

Clinical diagnosis of type 1 diabetes
Gold Score or Clarke Score ≥ 4 (highly associated with IAH)
Random non-fasting C-peptide \< 200 pmol/L
Diabetes duration ≥ 10 years
HbA1c \< 10.5%
Total Daily Insulin Dose of \< 1 unit/kg
Ability to read and speak English (because validated non-English versions of the cognitive tests and the educational interventions are not available)

Exclusion Criteria

Medical conditions that limit participation in study activities, as determined by the PI (including but not limited to cognitive dysfunction, reduced hearing, reduced vision, cancer under active treatment, untreated angina, organ failure)
Active alcohol or drug abuse (as defined by DSM criteria of either 1) recurrent use of alcohol/drugs resulting in a failure to fulfill major role obligations at work, school, or home, 2) recurrent alcohol/drug use in situations in which it is physically hazardous, or 3) recurrent alcohol or drug-related legal problems)
Social determinants of health that limit participation in study activities, as determined by the PI (including but not limited to homelessness, food insecurity, inadequate social support)
Seizure disorder unrelated to hypoglycemia associated seizures, unless documented seizure-free for \>12 months and on a stable regimen of anti-convulsant therapy
Skin conditions that would preclude the use of a CGM
Super-physiologic exposure to steroids within one month of enrollment
eGFR \< 45 mL/min/1.73 m2
History of bariatric surgery that irreversibly alters gut innervation and structure
Hyper- or hypokalemia (serum potassium \>5.5 or \<3.5 mmol/L)\
Hemoglobin \< 10 g/dL\
Medical condition that requires intermittent or continuous use of glucocorticoids at greater than physiological replacement doses
Pregnancy, plan for pregnancy, or breast feeding
Abnormal thyroid function tests of clinical significance, as determined by PI\
Liver transaminases \> 3 times the upper limit of normal\
Hospitalization for mental illness in last year
History of adrenalectomy
At discretion of the PI, laboratory tests may be repeated once. If the participant is not eligible after the second attempt, then the participant. The participant may be screened again.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Minneapolis?

Yes, this clinical trial (NCT06325202) has an active research site in Minneapolis, MN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Diabetes Mellitus, Type 1 Treatment Options in Minneapolis, MN

If you're searching for diabetes mellitus, type 1 treatment options in Minneapolis, MN, this clinical trial (NCT06325202) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Minneapolis research site is actively enrolling participants for this clinical trial. You'll receive care from experienced diabetes mellitus, type 1 specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all diabetes mellitus, type 1 clinical trials near you to find additional studies recruiting in your area.

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