San Antonio, TXNCT02969798Now EnrollingIRB Ready

Diabetes Mellitus, Type 2 Clinical Trial in San Antonio, TX

Access cutting-edge diabetes mellitus, type 2 treatment through this clinical trial at a research site in San Antonio. Study-provided care at no cost to qualified participants.

Sponsored by The University of Texas Health Science Center at San Antonio

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Expert Care in San Antonio

Access diabetes mellitus, type 2 specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related diabetes mellitus, type 2 treatment provided free

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Check if you qualify for this diabetes mellitus, type 2 clinical trial in San Antonio, TX

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to San Antonio

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit San Antonio site if eligible
  4. 4Begin participation

About This Diabetes Mellitus, Type 2 Study in San Antonio

HYPOTHESIS: Impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) have distinct pathophysiologic etiologies. Therefore, therapeutic interventions designed to correct the specific underlying pathogenic abnormalities in IGT and IFG will be required to optimally prevent the progressive beta cell failure and development of overt type 2 diabetes.

Sponsor: The University of Texas Health Science Center at San Antonio

Who Can Participate

Inclusion Criteria

NGT subjects will serve as controls and will be matched in age, gender, ethnicity, and BMI to IGT and IFG subjects
Male or female subjects between the ages of 18 and 65 years of age, inclusive, at Screening.
FPG \< 100 mg/dl and 2-h PG \< 140 mg/dl
BMI = 24-40 kg/m2;
Stable body weight (±4lbs) over the preceding 3 months
Subjects with no evidence of major organ system disease as determined by physical exam, history, and screening laboratory data
Females of childbearing potential with a negative pregnancy test at Screening and Treatment visits, using one of the following forms of contraception for the duration of participation in the study (i.e., until Follow-up 7-14 days post last dose):
Oral contraceptive
Injectable progesterone
Subdermal implant
Spermicidal foam/gel/film/cream/suppository
Diaphragm with spermicide
Copper or hormonal containing IUD
Sterile male partner vasectomized \> 6 month pre-dosing.
Evidence of a personally signed and dated informed consent document indicating that the subject has been informed of all pertinent aspects of the study.
Subjects must be willing and able to comply with scheduled visits, treatment, laboratory tests and study procedures.

Exclusion Criteria

Recent (i.e., within three (3) months prior to Screening) evidence or medical history of unstable concurrent disease such as: documented evidence or history of clinically significant hematological, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, psychiatric, immunological, or clinically significant neurological disease.
Subjects with a family history of diabetes in a first degree relative
BMI of less than 24 or greater than 40 kg/m2
Unstable body weight (change of greater than ±4lbs over the preceding 3 months
Subjects participating in an excessively heavy exercise program
Subject with a feeding/sleeping schedule different from a daytime feeding/night time sleeping schedule
Subjects taking medications known to alter glucose metabolism (with the exception of metformin and/or pioglitazone) or which effect brain neurosynaptic function are excluded.
Subjects with evidence of major organ system disease as determined by physical exam, history, and screening laboratory data
Pregnant subjects or subjects unwilling to use birth control during their study enrollment
Blood donation of approximately 1 pint (500 mL) within 8 weeks prior to Screening.
Other severe acute or chronic medical or psychiatric condition or laboratory abnormality that may increase the risk associated with study participation or investigational product administration or may interfere with the interpretation of study results and, in the judgment of the investigator, would make the subject inappropriate for entry into this study
Subjects with hematuria will be excluded.
Subjects with evidence or prior history of heart failure will be excluded
Subjects with family history of pancreatic, bladder, and breast cancer will be excluded.
Subjects with history of pancreatitis will be excluded.
Subjects with eGFR \< 60 ±5 ml/min.1.73m2 will be excluded.
Subjects with elevated serum creatinine (\>1.5 mg/dl males/1.4 mg/dl females) will be excluded.
Subjects with a history of orthostatic hypotension (\>15/10 mmHg) will be excluded.
Subjects with liver enzymes (ALT, AST) \>3-fold above upper normal limit will be excluded.
Subjects with a history of hypersensitivity to pioglitazone, dapagliflozin, or Saxagliptin will be excluded.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in San Antonio?

Yes, this clinical trial (NCT02969798) has an active research site in San Antonio, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Diabetes Mellitus, Type 2 Treatment Options in San Antonio, TX

If you're searching for diabetes mellitus, type 2 treatment options in San Antonio, TX, this clinical trial (NCT02969798) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our San Antonio research site is actively enrolling participants for this clinical trial. You'll receive care from experienced diabetes mellitus, type 2 specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all diabetes mellitus, type 2 clinical trials near you to find additional studies recruiting in your area.

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