Atlanta, GANCT07150546Now EnrollingIRB Ready

Digestive System Neuroendocrine Tumor Clinical Trial in Atlanta, GA

Access cutting-edge digestive system neuroendocrine tumor treatment through this phase 1 clinical trial at a research site in Atlanta. Study-provided care at no cost to qualified participants.

Sponsored by Emory University

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Expert Care in Atlanta

Access digestive system neuroendocrine tumor specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related digestive system neuroendocrine tumor treatment provided free

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Check if you qualify for this digestive system neuroendocrine tumor clinical trial in Atlanta, GA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Atlanta

    Convenient for GA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Atlanta site if eligible
  4. 4Begin participation

About This Digestive System Neuroendocrine Tumor Study in Atlanta

This phase I trial tests the safety and effectiveness of stereotactic body radiation therapy (SBRT) followed by 177Lu-DOTATATE peptide receptor radionuclide therapy (PRRT) in treating patients with large well-differentiated grade 1-2 digestive system neuroendocrine tumors that cannot be removed by surgery (unresectable). SBRT is a type of external radiation therapy that uses special equipment to position a patient and precisely deliver radiation to tumors in the body. The total dose of radiation is divided into smaller doses given over several days. This type of radiation therapy helps spare normal tissue. 177Lu-DOTATATE is a radioactive drug. It binds to a protein called somatostatin receptor, which is found on some neuroendocrine tumor cells. 177Lu-DOTATATE builds up in these cells and gives off radiation that may kill them. It is a type of radioconjugate and a type of somatostatin analog. Giving PRRT after SBRT may reduce the chances of the disease returning or getting worse, compared to the standard treatment of PRRT alone.

Sponsor: Emory University

Who Can Participate

Inclusion Criteria

Male or female
Age ≥ 18 years
Patient must be able to provide study specific informed consent
Pathologically confirmed neuroendocrine tumor fulfilling all of the following criteria
Well-differentiated, grade 1-2
Unresectable (prior resection is allowable), verified by tumor board or surgical oncology (surg onc)
Progression after one or two prior lines of systemic therapy
Somatostatin-receptor positive disease as determined by positive radiotracer-labeled DOTATATE PET/CT scan (modified Krenning score 3+)
One or more large lesions measuring 3 or more cm on contrast-enhanced CT or MRI
Eastern Cooperative Oncology Group (ECOG) performance status 0-2
Estimated glomerular filtration rate (GFR) \> 30 mL/min (within 90 days prior to study registration)
Total bilirubin ≤ 3 x upper limit of normal (within 90 days prior to study registration)
Albumin \> 30 g/L (within 90 days prior to study registration)
White blood cell (WBC) ≥ 2,000 cells/mm\^3 (within 90 days prior to study registration)
Platelets ≥ 70000 cells/mm\^3 (within 90 days prior to study registration)
Hemoglobin ≥ 8.0 g/dl (Note: The use of transfusion or other intervention to achieve hemoglobin \[Hgb\] ≥ 8.0 g/dl is acceptable.) (within 90 days prior to study registration)

Exclusion Criteria

Any prior radiation therapy including prior PRRT, external radiation, or Yttrium-90 radioembolization to the same site/region
Contraindications to radiation therapy including inflammatory bowel disease, systemic sclerosis, etc.
Brain metastases or any metastases extending into the spinal canal
Unable to obtain confirmation of payment coverage for any planned radiation treatment

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Atlanta?

Yes, this clinical trial (NCT07150546) has an active research site in Atlanta, GA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Digestive System Neuroendocrine Tumor Treatment Options in Atlanta, GA

If you're searching for digestive system neuroendocrine tumor treatment options in Atlanta, GA, this clinical trial (NCT07150546) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Atlanta research site is actively enrolling participants for this phase 1 clinical trial. You'll receive care from experienced digestive system neuroendocrine tumor specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

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Secure · Expert Care · Atlanta, GA