Charleston, SCNCT07137338Now EnrollingIRB Ready

Dilated Cardiomyopathy (DCM) Clinical Trial in Charleston, SC

Access cutting-edge dilated cardiomyopathy (dcm) treatment through this clinical trial at a research site in Charleston. Study-provided care at no cost to qualified participants.

Sponsored by Rocket Pharmaceuticals Inc.

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Expert Care in Charleston

Access dilated cardiomyopathy (dcm) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related dilated cardiomyopathy (dcm) treatment provided free

Apply for This Charleston Location

Check if you qualify for this dilated cardiomyopathy (dcm) clinical trial in Charleston, SC

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Charleston

    Convenient for SC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Charleston site if eligible
  4. 4Begin participation

About This Dilated Cardiomyopathy (DCM) Study in Charleston

This is a Phase 1, open-label, dose-escalation trial to characterize the safety, tolerability, and preliminary efficacy of RP-A701 following a single IV administration in high-risk adult patients with BAG3-DCM.

Sponsor: Rocket Pharmaceuticals Inc.

Who Can Participate

Inclusion Criteria

Subjects are eligible for inclusion into the study only if all the following criteria apply:
Male or female between 18 and 65 years of age at the time of signing the informed consent
Capable of and willing to provide signed informed consent
Clinical diagnosis of DCM defined as and requiring each of the following:
Mild to moderate systolic dysfunction (LVEF ≥ 25% and ≤ 45%) by echocardiography or CMR performed within 3 months of enrollment.
Absence of severe coronary artery disease (\>70% stenosis) or active myocardial ischemia as the etiology of LV systolic dysfunction
Absence of uncontrolled hypertension, significant cardiac valve disease (i.e., greater than moderate in severity), infiltrative disorder, or systemic disease known to cause cardiomyopathy.
Documentation of a pathogenic or likely pathogenic variant in BAG3
History of ICD implantation ≥ 3 months prior to enrollment
NYHA Class II or III HF symptoms with stable HF therapeutic guideline-directed medical regimen for 30 days prior to enrollment

Exclusion Criteria

CV disease that may be related to a genetic etiology other than a BAG3 pathogenic or likely pathogenic variant.
Previous participation in a study of gene transfer or gene editing.
I.V. inotropic, vasodilator, or diuretic therapy ≤ 30 days prior to enrollment.
History of intracardiac thrombosis or arterial thromboembolic events
Severe RV dysfunction assessed by echocardiogram or CMR ≤ 12 months prior to screening
LVEF \< 25% by echocardiogram or CMR at ≤ 3 months prior to screening
NYHA Class I or IV HF

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Charleston?

Yes, this clinical trial (NCT07137338) has an active research site in Charleston, SC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Dilated Cardiomyopathy (DCM) Treatment Options in Charleston, SC

If you're searching for dilated cardiomyopathy (dcm) treatment options in Charleston, SC, this clinical trial (NCT07137338) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Charleston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced dilated cardiomyopathy (dcm) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all dilated cardiomyopathy (dcm) clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Charleston, SC