Snellville, GANCT07135167Now EnrollingIRB Ready

Down Syndrome (DS) Clinical Trial in Snellville, GA

Access cutting-edge down syndrome (ds) treatment through this clinical trial at a research site in Snellville. Study-provided care at no cost to qualified participants.

Sponsored by Woolfson Eye Institute

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Expert Care in Snellville

Access down syndrome (ds) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related down syndrome (ds) treatment provided free

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Check if you qualify for this down syndrome (ds) clinical trial in Snellville, GA

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Why Participate?

  • No-Cost Study Care

  • Local to Snellville

    Convenient for GA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Snellville site if eligible
  4. 4Begin participation

About This Down Syndrome (DS) Study in Snellville

The goal of this clinical trial is to study the effects of an experimental (not Food and Drug Administration (FDA)-approved) treatment called corneal crosslinking (CXL) for conditions in which the cornea becomes progressively thin, steep, and misshapen, causing vision to be blurred. CXL is performed by putting riboflavin (vitamin B2) drops onto the eye and then exposing it to ultraviolet (UVA) light at about the same intensity as you get outdoors on a bright, sunny day. It is designed to stop the progression of disease by strengthening the cornea. Study participants will be 8 years of age or older and have a diagnosis of Down syndrome. The main question it aims to answer is: * Does CXL help prevent or slow the progression of someone's corneal condition and vision loss? Participants will: * Attend up to a total of 7 in office visits over the course of 6 months, where several eye and vision tests will be given. Receive CXL (applying riboflavin (Vitamin B2 eye drops) to the eye, then exposing the eye to ultraviolet (UV-A) light for 20 minutes).

Sponsor: Woolfson Eye Institute

Who Can Participate

Inclusion Criteria

Be at least 8 years of age or older, male or female, of any race.
Have a diagnosis of Down syndrome or other cognitive, developmental, or medical conditions that precludes the subject from reliably following instructions or performing some of the study examination procedures.
Have a diagnosis of keratoconus, pellucid marginal degeneration, progressive ectasia after previous CXL treatment, other ectatic condition, or forme fruste keratoconus based on topography, tomography, and slit lamp examination.
Provide written informed consent and a signed HIPAA form. Pediatric subjects less than 14 years of age must sign an assent, and a parent or legal guardian must sign an informed consent. If the subject has impaired consent capacity, determined by the consenter, the consent form must be signed by the subject's legally authorized representative on behalf of the subject.
Satisfactory completion of the standardized clinical decision tool evaluation of patient suitability for CXL. (See Section 7.2.3)
Be willing and able to follow all instructions to the best of his/her abilities and comply with the schedule for follow-up visits.

Exclusion Criteria

Normal corneal topography.
A history of previous corneal transplant in the study eye.
Minimum corneal thickness \< 300 (measured by Pentacam and Ultrasound) at the screening exam.
Previous ocular condition (other than refractive error) in the eye(s) to be treated that may predispose the eye to future complications or prevent the possibility of improved vision, for example:
History of, or active, corneal disease (e.g., herpes simplex, herpes zoster keratitis, etc.)
Clinically significant corneal scarring in the central cornea that, in the investigator's opinion, will not allow the subject to achieve functional vision, even with contact lens correction, after the crosslinking procedure.
A known contraindication, sensitivity, or allergy to the test article or its components or to study medications.
Nystagmus or any other condition that would prevent a steady gaze during the crosslinking treatment or other diagnostic tests.
If female, pregnant, lactating or planning a pregnancy, or having a positive urine pregnancy test prior to the randomization of, or treatment of either eye during the course of the study. \[NOTE: If female and capable of becoming pregnant, must agree to use a medically acceptable form of birth control for at least one week prior to the treatment visit and to continue one month following treatment. \] 7\. Inability to remove soft or scleral contact lenses at least 3 days before initial and follow-up examinations. 8\. Inability to remove rigid gas-permeable contact lenses at least 2 weeks before initial and follow-up examinations. 9\. Inability to return for required postoperative examinations. 10. Presence or history or any other condition or finding that, in the investigator's opinion, makes the subject unsuitable as a candidate for crosslinking or study participation or may confound the outcome of the study.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Snellville?

Yes, this clinical trial (NCT07135167) has an active research site in Snellville, GA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Down Syndrome (DS) Treatment Options in Snellville, GA

If you're searching for down syndrome (ds) treatment options in Snellville, GA, this clinical trial (NCT07135167) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Snellville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced down syndrome (ds) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all down syndrome (ds) clinical trials near you to find additional studies recruiting in your area.

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