Boston, MANCT03868293Now EnrollingIRB Ready

Drug Resistant Epilepsy Clinical Trial in Boston, MA

Access cutting-edge drug resistant epilepsy treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Brigham and Women's Hospital

Quick Self-Assessment

See if you qualify for this Boston location

Preparing your pre-screening questions…

Expert Care in Boston

Access drug resistant epilepsy specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related drug resistant epilepsy treatment provided free

Apply for This Boston Location

Check if you qualify for this drug resistant epilepsy clinical trial in Boston, MA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Drug Resistant Epilepsy Study in Boston

The aim of the proposed pilot study is to investigate patient tolerability and efficacy of moderate term, repeated exposure of Pulsed Low-Intensity Focused Ultrasound (PLIFUS) in patients with drug-resistant temporal lobe epilepsy.

Sponsor: Brigham and Women's Hospital

Who Can Participate

Inclusion Criteria

Subjects at least eighteen (18) years of age
Subjects with drug-resistant temporal lobe epilepsy whose seizures involve altered awareness (ie failed at least two trials of antiepileptic drugs for seizures), as determined by one of the BWH epilepsy neurologists based on clinical seizure semiology and/or EEG findings.
Subjects who experience at least 1-2 seizures per month on average, are aware of or have reliable caregivers who are aware of when seizures occur and can reliably log seizure frequency
Subjects who have the cognitive ability to read and understand the consent form, describe any potential symptoms experienced during or after treatments.

Exclusion Criteria

Subjects with a cognitive or psychiatric disorder that limits the ability to give informed consent or are unable to cooperate with testing
Subjects with dementia or other progressive degenerative disease, delirium or active psychosis
Subjects with ferromagnetic materials in the head
Subjects with severe cardiac disease, increased intracranial pressure, or a Transcutaneous Electrical Nerve Stimulation (TENS) unit
Subjects who have primary generalized epilepsy or non-epileptic seizures
Subjects who have experienced status epilepticus in the 3 months leading up to enrollment in the study
Subjects (females) who are pregnant, or are of childbearing potential and not willing to use reliable birth control during the treatment period.
Subjects who are unable to get a brain MRI for any reason (implanted metal in body, inability to lie still)
Subjects with current brain tumors or an intracranial vascular lesion
Subjects with severe, uncontrolled medical problems, such as diabetes mellitus, hypertension, pulmonary or airway disease, heart failure, coronary artery disease, or any other condition that poses a risk for the subject during participation.
Subjects with holes in the treatment area of the skull from trauma or prior surgery
Subjects with pacemakers, medication pumps, and other implanted electronic hardware. If a subject has a working Vagal Nerve Stimulator in place, the device will be turned off prior to each treatment session and then turned back on after each session.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT03868293) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Drug Resistant Epilepsy Treatment Options in Boston, MA

If you're searching for drug resistant epilepsy treatment options in Boston, MA, this clinical trial (NCT03868293) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced drug resistant epilepsy specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all drug resistant epilepsy clinical trials near you to find additional studies recruiting in your area.

More Epilepsy Trials in Boston, MA

See all epilepsy clinical trials recruiting in Boston — not just this study.

Browse Epilepsy Trials in Boston →

Browse More Trials by Condition

Epilepsy TrialsAll Conditions →

Ready to Join in Boston?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Boston, MA