Durham, NCNCT07764718Now EnrollingIRB Ready

Drug-Resistant Focal Epilepsy Clinical Trial in Durham, NC

Access cutting-edge drug-resistant focal epilepsy treatment through this clinical trial at a research site in Durham. Study-provided care at no cost to qualified participants.

Sponsored by Duke University

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Expert Care in Durham

Access drug-resistant focal epilepsy specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related drug-resistant focal epilepsy treatment provided free

Apply for This Durham Location

Check if you qualify for this drug-resistant focal epilepsy clinical trial in Durham, NC

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Durham

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Durham site if eligible
  4. 4Begin participation

About This Drug-Resistant Focal Epilepsy Study in Durham

This study evaluates whether a non-invasive brain stimulation technique called Temporal Interference (TI) can reduce epilepsy-related abnormal brain activity and influence sleep-related brain rhythms in adults with focal drug-resistant epilepsy undergoing stereo-EEG monitoring for clinical care. Up to 30 participants will complete stimulation sessions during wakefulness and, when possible, natural non-REM sleep. Brain activity will be recorded using scalp EEG and implanted sEEG electrodes before, during, and after TI stimulation. Some participants may also receive subthreshold direct stimulation through implanted electrodes for comparison. The study aims to determine whether TI can reduce epilepsy biomarkers, alter sleep-related brain activity, and compare favorably with conventional direct electrical stimulation while remaining within established safety limits.

Sponsor: Duke University

Who Can Participate

Inclusion Criteria

Adult patients with focal DRE who will undergo presurgical evaluation with sEEG
Availability of at least one sEEG electrode inserted into the thalamus for clinical purposes
sEEG performed with the indication to identify one single epileptic focus
Ability to provide written informed consent and comply with the study protocol

Exclusion Criteria

\- Remote resective/ablative brain surgery

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Durham?

Yes, this clinical trial (NCT07764718) has an active research site in Durham, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Drug-Resistant Focal Epilepsy Treatment Options in Durham, NC

If you're searching for drug-resistant focal epilepsy treatment options in Durham, NC, this clinical trial (NCT07764718) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Durham research site is actively enrolling participants for this clinical trial. You'll receive care from experienced drug-resistant focal epilepsy specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all drug-resistant focal epilepsy clinical trials near you to find additional studies recruiting in your area.

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