Dallas, TXNCT03428009Now EnrollingIRB Ready

Dystonia Clinical Trial in Dallas, TX

Access cutting-edge dystonia treatment through this clinical trial at a research site in Dallas. Study-provided care at no cost to qualified participants.

Sponsored by University of Texas Southwestern Medical Center

Quick Self-Assessment

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Expert Care in Dallas

Access dystonia specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related dystonia treatment provided free

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Check if you qualify for this dystonia clinical trial in Dallas, TX

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Dallas

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Dallas site if eligible
  4. 4Begin participation

About This Dystonia Study in Dallas

The purpose of this study is to (1) investigate the effect of known dystonia-causing mutations on brain structure and function, to (2) identify structural brain changes that differ between clinical phenotypes of dystonia, and to (3) collect DNA, detailed family history, and clinical phenotypes from patients with idiopathic dystonia with the goal of identifying new dystonia-related genes. Investigators will be recruiting both healthy control subjects and subjects with any form of dystonia. For this study there will be a maximum of two study visit involving a clinical assessment, collection of medical and family history, task training session, an MRI using the learned tasks, and finally a blood draw for genetic analysis. In total, these visits will take 3-5 hours. If the dystonia subjects receive botulinum toxin injections for treatment, the participants and their matched controls will be asked to come for a second visit.

Sponsor: University of Texas Southwestern Medical Center

Who Can Participate

Inclusion Criteria

Dystonia group Previous diagnosis of dystonia which include but is not limited to:
cervical dystonia (50 subjects)
blepharospasm (25 subjects)
limb dystonia (50 subjects)
spasmodic dysphonia (25 subjects)
segmental dystonia
multi-focal dystonia
Any childhood-onset dystonia (25 subjects) Age \> 11 years
Control group: No prior dystonia diagnosis (175 subjects) Age \> 11 years

Exclusion Criteria

(both Dystonia and Control groups):
Metal in any part of the body (including metal injury to the eye) OR carrying a medical device incompatible with MRI (e.g., metal implants such as surgical clips or pacemakers) OR positive screening per UTSW MRI screening form
Claustrophobia
Non-fluent English
Weight incompatible with MRI safety
History of head trauma with neurological sequelae, including multiple concussions and/or history of stroke
Serious medical illness or history of serious medical illness, including cancer that was treated with radiation or chemotherapy, heart attack, or a known history of HIV-1 + status
Subjects with Hepatitis C (by Hepatitis C+ titer)
Subjects with insulin dependent diabetes mellitus (IDDM)
Severe respiratory compromise
In the opinion of the investigator, not able to safely participate in this study Inclusion Criteria:
Dystonia group Previous diagnosis of dystonia which include but is not limited to:
cervical dystonia (50 subjects)
blepharospasm (25 subjects)
limb dystonia (50 subjects)
spasmodic dysphonia (25 subjects)
segmental dystonia
multi-focal dystonia
Any childhood-onset dystonia (25 subjects) Age \> 11 years
Control group: No prior dystonia diagnosis (175 subjects) Age \> 11 years Exclusion Criteria:
Dystonia group Prior history of or concurrent neurological or psychiatric diagnosis - depression and/or anxiety accepted Current use of non-dystonia neuroactive medications - SSRI/medication for depression and/or anxiety accepted Current use of cervical brace designed for dystonia treatment Prior structural brain injury Control group: History of or current neurological or psychiatric diagnosis - depression and/or anxiety accepted, but must not be in active phase Current use of any neuroactive medication, SSRI/medication for depression and/or anxiety accepted

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Dallas?

Yes, this clinical trial (NCT03428009) has an active research site in Dallas, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Dystonia Treatment Options in Dallas, TX

If you're searching for dystonia treatment options in Dallas, TX, this clinical trial (NCT03428009) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Dallas research site is actively enrolling participants for this clinical trial. You'll receive care from experienced dystonia specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

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Secure · Expert Care · Dallas, TX