NCT05906082 · Jovan Gwon, PhD, RN, FIAAN
Vape-Free Text-Messaging: Pilot Study
What this study is about
This is a small pilot randomly assigned controlled trial to evaluate the feasibility, acceptability, and preliminary effectiveness of the e-cigarette cessation text-messaging intervention with young adults in rural areas.
View original scientific description
This is a small pilot randomized controlled trial to evaluate the feasibility, acceptability, and preliminary efficacy of the e-cigarette cessation text-messaging intervention with young adults in rural areas.
Interventions
BEHAVIORAL
E-cigarette cessation text-messaging intervention
This is the intervention for e-cigarette cessation using text messages targeting young adults in rural areas.
BEHAVIORAL
Standard care control using standard national resources
This is the standard care with national resources from smokefree.gov.
Primary outcome measures
Number of participants recruited and randomized
Time frame: Throughout 12 months
Number of participants recruited and randomized
Self-reported proportion of text messages read
Time frame: At 1 month
Proportion of text messages read during the intervention or standard care at 1 month
Retention rates (proportion of participants remained until 1 month post-intervention from enrollment)
Time frame: At 1 month
Proportion of participants from enrollment to 1 month post-intervention or standard-care
Level of acceptability of the intervention
Time frame: At 1 month
1. When you had received our text messages from our VapeFreeTXT program 1 month ago, how many of our text messages did you read on a typical day? Not at all (1) Read about 25% messages (2) Read about half messages (3) Read about 75% messages (4) Read the entire messages (5) 2. How useful was our VapeFreeTXT program in helping you quit vaping? Not at all useful (1) Slightly useful (2) Moderately useful (3) Very useful (4) Extremely useful (5) 3. Did our VapeFreeTXT program make you think about quitting vaping? Not at all (1) Probably not (2) Neither yes nor no (3) Probably yes (4) Definitely yes (5) 4. Do you think our VapeFreeTXT program will change your vaping? Not at all (1) Probably not (2) Neither yes nor no (3) Probably yes (4) Definitely yes (5) 5. Would you recommend this program to a friend or others? Not at all (1) Probably not (2) Neither yes nor no (3) Probably yes (4) Definitely yes (5)
Proportion of salivary cotinine samples returned
Time frame: At 1 month
Proportion of salivary cotinine samples returned to the office lab for cotinine analysis
Self-reported 7-days point prevalence abstinence from ENDS and other tobacco
Time frame: At 1 month
Self-reported 7-days point prevalence abstinence from ENDS and other tobacco
Concentration of cotinine in saliva
Time frame: At 1 month
Biochemically verified abstinence evaluated by salivary cotinine samples
Nicotine dependence (Penn State Electronic Cigarette Dependence Index)
Time frame: At 1 month
Nicotine dependence (minimum 0 to maximum 20, higher scores mean a worse outcome.)
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- English speaking
- 18-24 years
- everyday e-cigarette use in the past month
- ownership of a mobile phone or smartphone with texting and internet access abilities
- knowledge of how to use text messages
- plan on quitting e-cigarette use within one month
- home address in a rural county of Wisconsin, Minnesota, North Dakota, and South Dakota
Exclusion criteria
- Individuals who reported use of other tobacco products (e.g., cigarettes, smokeless tobacco) than e-cigarettes in the past month
Where
- Milwaukee, Wisconsin
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Aug 7, 2025 · Source of record for eligibility and locations