La Jolla, CANCT05231785Now EnrollingIRB Ready

Early-Onset Alzheimer Disease Clinical Trial in La Jolla, CA

Access cutting-edge early-onset alzheimer disease treatment through this phase 1 clinical trial at a research site in La Jolla. Study-provided care at no cost to qualified participants.

Sponsored by Alnylam Pharmaceuticals

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Expert Care in La Jolla

Access early-onset alzheimer disease specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related early-onset alzheimer disease treatment provided free

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Check if you qualify for this early-onset alzheimer disease clinical trial in La Jolla, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to La Jolla

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit La Jolla site if eligible
  4. 4Begin participation

About This Early-Onset Alzheimer Disease Study in La Jolla

The purpose of this study is to evaluate the safety, tolerability, pharmacodynamics (PD) and pharmacokinetics (PK) of a single dose and multiple doses of ALN-APP administered by intrathecal (IT) injection in adult patients with early-onset Alzheimer's Disease (EOAD). Maximum treatment duration for Part A: single dose. Maximum treatment duration for Part B: 12 months.

Sponsor: Alnylam Pharmaceuticals

Who Can Participate

Inclusion Criteria

Has mild cognitive impairment or mild dementia due to EOAD
Has Clinical Dementia Rating (CDR) global score 0.5 or 1.0 and Mini Mental State Examination (MMSE) \>20

Exclusion Criteria

Has Non-Alzheimer's disease dementia
Has alanine aminotransferase (ALT) or aspartate aminotransferase (AST) \>2×upper limit of normal (ULN)
Has estimated glomerular filtration rate (eGFR) \<45 mL/min/1.73m\^2 at Screening
Has recently received an investigational agent
Has recent treatment with amyloid-targeting antibody Note: other protocol defined inclusion / exclusion criteria apply

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in La Jolla?

Yes, this clinical trial (NCT05231785) has an active research site in La Jolla, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Early-Onset Alzheimer Disease Treatment Options in La Jolla, CA

If you're searching for early-onset alzheimer disease treatment options in La Jolla, CA, this clinical trial (NCT05231785) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our La Jolla research site is actively enrolling participants for this phase 1 clinical trial. You'll receive care from experienced early-onset alzheimer disease specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all early-onset alzheimer disease clinical trials near you to find additional studies recruiting in your area.

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