Winston Salem, NCNCT05828823Now EnrollingIRB Ready

End-Stage Kidney Disease Clinical Trial in Winston Salem, NC

Access cutting-edge end-stage kidney disease treatment through this clinical trial at a research site in Winston Salem. Study-provided care at no cost to qualified participants.

Sponsored by Wake Forest University Health Sciences

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Expert Care in Winston Salem

Access end-stage kidney disease specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related end-stage kidney disease treatment provided free

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Check if you qualify for this end-stage kidney disease clinical trial in Winston Salem, NC

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Winston Salem

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Winston Salem site if eligible
  4. 4Begin participation

About This End-Stage Kidney Disease Study in Winston Salem

This study is to prospectively compare clinical effectiveness between clinically- matched incremental hemodialysis and conventional hemodialysis in patients with incident kidney dysfunction requiring dialysis and residual kidney function. The study will enroll 350 patients on chronic hemodialysis and 140 caregivers of enrolled patients. Patients will be randomized in 1:1 ratio to either incremental start hemodialysis or conventional hemodialysis. Caregivers will be followed along with patients for an average period of 2 years post randomization.

Sponsor: Wake Forest University Health Sciences

Who Can Participate

Inclusion Criteria

Clinical Inclusion Criteria:
Age ≥ 18 years
Incident kidney dysfunction requiring dialysis (KDRD) started on maintenance, in-center hemodialysis (HD), or anticipated to be started on maintenance, in-center HD within the next 12 weeks
Has received ≤36 sessions of intermittent HD (i.e., on HD for ≤12 weeks) at the time patient is approached for potential study participation Residual Kidney Function Inclusion Criteria:
Kidney urea clearance \<2.0 mL/min
Urine volume# of ≥500 mL/24 h

Exclusion Criteria

Pre-HD serum K ≥5.8 mEq/L, Na ≤125 mEq/L, or bicarbonate level ≤17 mEq/L
Requirement or anticipated requirement of high-volume ultrafiltration
Unable or unwilling to follow the study protocol for any reason
Known pregnancy or planning to attempt to become pregnant or lactating women
Estimated survival or dialysis modality change or center transfer \<6 months Caregiver Eligibility Criteria:
be at least 18 years old
be the main caregiver (at patient's choice)
be a close relative of the patient (spouse, child, sibling, parent, grandchild)
have no known psychiatric and neurologic disorders (through direct inquiry from the person)
not be a member of the medical or healthcare team
not be the caregiver for another patient with chronic illness
not have experienced severe life events within prior 3 months of enrollment (through direct inquiry from the person)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Winston Salem?

Yes, this clinical trial (NCT05828823) has an active research site in Winston Salem, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

End-Stage Kidney Disease Treatment Options in Winston Salem, NC

If you're searching for end-stage kidney disease treatment options in Winston Salem, NC, this clinical trial (NCT05828823) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Winston Salem research site is actively enrolling participants for this clinical trial. You'll receive care from experienced end-stage kidney disease specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all end-stage kidney disease clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Winston Salem, NC