NCT07014111 · University of Illinois at Chicago
Fight Fatigue: A Progressive Muscle Relaxation and Walking Intervention to Reduce Fatigue in Adults With ESKD
What this study is about
Fight Fatigue is evaluating the feasibility and acceptability of a combined progressive muscle relaxation and walking intervention to reduce fatigue for adults with end-stage kidney disease receiving in-center hemodialysis.
View original scientific description
Fight Fatigue is evaluating the feasibility and acceptability of a combined progressive muscle relaxation and walking intervention to reduce fatigue for adults with end-stage kidney disease receiving in-center hemodialysis.
Interventions
BEHAVIORAL
Fight Fatigue
Combined progressive muscle relaxation and walking (increasing step count) 12-week intervention that consists of education/training followed by text messages.
OTHER
Attention Control
End-stage kidney disease education
Primary outcome measures
Feasibility of recruitment
Time frame: Baseline to week 12
Recruitment metrics (enrolled/invited)
Feasibility of retention
Time frame: Baseline to week 12
Retention in the study from baseline to week 12
Acceptability
Time frame: End of study (Week 12)
Participant rating of acceptability (e.g., enjoyable, easy to understand) via Likert scale questions and open ended questions
Adherence to the study protocol
Time frame: Baseline to week 12
Adherence to the intervention measured with adherence to step counts, number/duration of accesses on the study-specific website, and adherence to study procedures as evaluated with number of text messages read/sent messages read.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Diagnosis of ESKD diagnosis and receiving hemodialysis for at least 3 months
- Can read and speak English
- Fatigue measured via visual analogue scale, score ≥4 over the last week
- Able to stand and walk one block
- Has a cell phone that can receive text messages
Exclusion criteria
- Patient's nephrologist refuses for them to participate
- Unstable angina
- Unstable pulmonary disease or pulmonary symptoms that preclude participation
- Lower-extremity amputation without prosthetic (BKA, AKA) -Orthopedic or neurologic condition that would preclude walking or tensing/releasing of muscles-
- Cognitive impairment that, in the judgement of the research team, precludes trial participation
- Participation in the formative phase of the development of Fight Fatigue
Where
- Chicago, Illinois
Collaborators
National Center for Complementary and Integrative Health (NCCIH)
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Sep 26, 2025 · Source of record for eligibility and locations