University Park, PANCT05069740Now EnrollingIRB Ready

Endometriosis Clinical Trial in University Park, PA

Access cutting-edge endometriosis treatment through this clinical trial at a research site in University Park. Study-provided care at no cost to qualified participants.

Sponsored by Penn State University

Quick Self-Assessment

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Expert Care in University Park

Access endometriosis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related endometriosis treatment provided free

Apply for This University Park Location

Check if you qualify for this endometriosis clinical trial in University Park, PA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to University Park

    Convenient for PA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit University Park site if eligible
  4. 4Begin participation

About This Endometriosis Study in University Park

The purpose of this study is to better understand the underlying mechanisms associated with elevated cardiovascular disease risk in women with endometriosis, and to measure the effectiveness of emerging endometriosis treatments on outcomes specific to cardiovascular dysfunction. Epidemiologic data demonstrate a clear association between endometriosis, reproductive risk factors, inflammation and cardiovascular (CV) risk. Circulating factors, low-density lipoprotein (LDL) and oxidized LDL (oxLDL), are two of many biomarkers of cardiovascular and inflammatory disease of endometriosis. An important signaling mechanism through which circulating LDL and oxLDL act is the lectin-like oxidized LDL receptor (LOX-1). LOX-1 signal transduction functionally results in pronounced endothelial dysfunction, a hallmark of CV. The investigators hypothesis that one factor mediating the elevated risk of cardiovascular disease in endometriosis is systemic inflammation and activation of LOX-1 receptor mechanisms.

Sponsor: Penn State University

Who Can Participate

Inclusion Criteria

Healthy women between the ages of 18 and 45 years (Controls), taking oral contraceptive or with regular menses every 26-34 days
Women between the ages of 18 and 45 years with endometriosis (diagnosis by prior laparoscopy by subject's own physician \<5 years prior, and reported by the subject to the researchers)
Tylenol if the subject has acute pain is allowed
Contraceptive use is allowed

Exclusion Criteria

Use of nicotine-containing products (e.g. smoking, chewing tobacco, etc.)
Diabetes (HbA1C 6.5%)
Taking pharmacotherapy that could alter peripheral vascular control (e.g. insulin sensitizing, cardiovascular medications)
Breastfeeding
Taking illicit and/or recreational drugs
Abnormal liver function
Rash, skin disease, disorders of pigmentation, known skin allergies
Diagnosed or suspected metabolic or cardiovascular disease
Persistent unexplained elevations of serum transaminases
Known allergy to latex or investigative substances (including salsalate or simvastatin)
History of gastrointestinal bleeding

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in University Park?

Yes, this clinical trial (NCT05069740) has an active research site in University Park, PA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Endometriosis Treatment Options in University Park, PA

If you're searching for endometriosis treatment options in University Park, PA, this clinical trial (NCT05069740) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our University Park research site is actively enrolling participants for this clinical trial. You'll receive care from experienced endometriosis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all endometriosis clinical trials near you to find additional studies recruiting in your area.

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